Temperature and myocardial infarction among migrants in Kuwait.

Background: Kuwait, one of the world's hottest countries, faces increasing temperatures due to climate change. With a large migrant population predominantly employed in physically demanding jobs, the exact effects and burdens of temperature exposure on cardiovascular risk among this population remain unknown. This study aimed to investigate the relationship between temperature and myocardial infarction (MI) risk among migrants in Kuwait.

Prognostic role of prostate specific antigen kinetics in primary high volume metastatic hormonal sensitive prostate cancer treated with novel hormonal therapy agents.

The prognostic value of prostate-specific antigen (PSA) kinetics in primary high-volume metastatic hormone-sensitive prostate cancer (mHSPC) patients treated with novel hormonal therapy agents is still unclear. Here, we retrospectively reviewed the data of 102 patients with primary high-volume mHSPC who received novel hormonal therapy agents. The median follow-up was 32.

A hybrid RSM-BPNN-GA approach for optimizing ultrasound-assisted deep eutectic solvents extraction conditions for Mesona chinensis benth. and investigation of the extraction mechanism.

Mesona chinensis Benth (MCB) is the source of the most commonly consumed herbal beverage in Southeast Asia and China and is thus an economically important agricultural plant. Therefore, optimal extraction and production procedures have significant commercial value. Currently, in terms of green chemistry, researchers are investigating the use of greener solvents and innovative extraction techniques to increase extract yields.

Neutrophil extracellular traps facilitate sympathetic hyperactivity by polarizing microglia toward M1 phenotype after traumatic brain injury.

Traumatic brain injury (TBI), particularly diffuse axonal injury (DAI), often results in sympathetic hyperactivity, which can exacerbate the prognosis of TBI patients. A key component of this process is the role of neutrophils in causing neuroinflammation after TBI by forming neutrophil extracellular traps (NETs), but the connection between NETs and sympathetic excitation following TBI remains unclear. Utilizing a DAI rat model, the current investigation examined the role of NETs and the HMGB1/JNK/AP1 signaling pathway in this process.

Implementation of the real-virtual 3D scene-fused full-parallax holographic stereogram.

This work focuses on the generation of three-dimensional (3D)-scene information as well as the fusion of real and virtual 3D scene information for the full-parallax holographic stereogram based on the effective perspective images' segmentation and mosaicking (EPISM) method. The improved depth-image-based rendering (DIBR) method was used to generate the virtual viewpoint images of the real 3D scene, and the regularization and densification processing models of the degraded light field were established; as a result, the real sampling-light field was reconstructed. Combined with the computer-rendered virtual 3D scene information, a "real + virtual" light-field fusion method based on a pixel-affine-projection was proposed to realize the fusion of the real and virtual 3D scene.

View-flipping effect reduction and reconstruction visualization enhancement for EPISM based holographic stereogram with optimized hogel size.

To reduce the view-flipping effect and enhance the viewing resolution, the modulation characteristics of the hogel based holographic stereogram is constructed and validated. The performance of the view-flipping effect is analyzed, and the results indicate that decreasing the size of hogel is beneficial to the reduction of the view flipping, however, which will result in significant diffraction effect which can degrade the reconstruction quality. Furthermore, a diffraction-limited imaging model of the hogel based holographic stereogram is established, where both the limited aperture of the hogel and the defocused aberration of the object point are introduced, and the effective resolvable size of the reconstructed image point is simulated.

Analysis on the reconstruction error of EPISM based full-parallax holographic stereogram and its improvement with multiple reference plane.

To reduce the reconstruction error of holographic stereogram fabricated by effective perspective images' segmentation and mosaicking method (EPISM), a multiple-reference-plane (MRP) approach is proposed and validated. The reconstruction error for traditional EPISM is analyzed, and the results indicate that the distortion as well as the blur will be involved for object points located far away from the reference plane. A new method by introducing multiple reference planes is proposed, which divides the 3D scene into several parts along its depth direction, and sets a reference plane for each of the object part.

miR-145 inhibits invasion of bladder cancer cells by targeting PAK1.

Objectives: MicroRNAs play important roles in cancer. In many cancers, miR-145 acts as a tumor suppressor, and it is down-regulated in bladder cancer. In the present study, we explored the modulation of oncogenic gene PAK1 by miR-145 in bladder cancer.