Visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N electron donor-acceptor complexes.

A visible-light-promoted azidation/arylation of unactivated alkenes with Togni-N has been achieved, leading to a series of azidated pyrrolo[1,2-]indoles under photocatalyst-free conditions. Notably, an EDA complex derived from the electron-rich indole derivatives and Togni-N served as the key intermediate in this reaction.

Enhancement of ε-poly-L-lysine production by Streptomyces albulus FQF-24 with feeding strategies using cassava starch as carbon source.

ε-Poly-L-lysine (ε-PL) is a natural and wide-spectrum antimicrobial additive. In this study, the production of ε-PL by Streptomyces albulus FQF-24 using cassava starch (CS) as carbon source and the effects of different feeding methods were investigated in a fermenter. The initial shake flask experiments demonstrated the efficient production of ε-PL with CS, achieving the ε-PL production of 1.

The inhibitory mechanism of echinacoside against Staphylococcus aureus Ser/Thr phosphatase Stp1 by virtual screening and molecular modeling.

Context: Stp1 is a new potential target closely related to the pathogenicity of Staphylococcus aureus (S. aureus). In this study, effective Stp1 inhibitors were screened via virtual screening and enzyme activity experiments, and the inhibition mechanism was analyzed using molecular dynamics simulation.

Efficient production of ε-poly-l-lysine using cassava starch and fish meal by FQC-24.

ε-Poly-l-lysine (ε-PL) is used as a natural food preservative which consists of l-lysine units connected. However, due to the expensive culture medium, the production cost of ε-PL remains high. In this study, cheap raw materials cassava starch (CS) and fish meal (FM) were employed by FQC-24 for ε-PL production.

Mesoporous silica nanoparticles loaded with capsaicin and their oxidation resistance in meat preservation.

In this work, capsaicin (CAP) was loaded into mesoporous silica nanoparticles (MSNs) with grain diameters of 50 nm, 100 nm and 400 nm by free diffusion to obtain the support materials Cap@MSN-50, Cap@MSN-100 and Cap@MSN-400, respectively. The loading capacity was separately calculated as 854.77, 713.