Publications by authors named "Chenlei Guo"

Microorganisms are the dominant players driving the degradation and transformation of chloramphenicol (CAP) in the environment. However, little bacterial strains are able to efficiently degrade and mineralize CAP, and the CAP degrading pathways mediated by oxidative reactions remain unclear. In this study, a highly efficient CAP-degrading microbial consortium, which mainly consists of Rhodococcus (relative abundance >70%), was obtained through an enrichment process using CAP-contaminated activated sludge as the inoculum.

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Background And Purpose: Along with the increasing demand for high-quality radiotherapy and the growing number of high-precision radiotherapy devices, precise radiotherapy workflow management and accurate time evaluation of the entire radiotherapy process are crucial to providing appropriate, timely treatment for cancer patients. This study therefore aimed to establish an accurate, reliable method for evaluating the duration of the radiotherapy process, from beginning to end, based on real-time measurement data. These data are vital for improving the quality and efficiency of radiotherapy delivery.

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Purpose: To investigate planning time and number of optimizations in routine clinical lung cancer plans based on the plan quality improvements following each optimization.

Materials And Method: We selected 40 patients with lung cancer who were treated with conventional fractionated radiotherapy (CFRT). The 40 plans (divided into two groups with one or two target volumes) were completed by 9 planners using volumetric modulated arc therapy (VMAT).

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To introduce a beam angle selection method based on the patient coordinate system for treatment planning of noncoplanar intensity-modulated radiation therapy (IMRT). Traditionally, in radiotherapy planning, beam directions are selected in the machine coordinate system. A noncoplanar beam direction is established through a treatment table rotation followed by a gantry rotation.

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We present a methodology for the automatic identification and delineation of germ-layer components in H&E stained images of teratomas derived from human and nonhuman primate embryonic stem cells. A knowledge and understanding of the biology of these cells may lead to advances in tissue regeneration and repair, the treatment of genetic and developmental syndromes, and drug testing and discovery. As a teratoma is a chaotic organization of tissues derived from the three primary embryonic germ layers, H&E teratoma images often present multiple tissues, each of having complex and unpredictable positions, shapes, and appearance with respect to each individual tissue as well as with respect to other tissues.

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In this paper, we develop a robust signal space separation (rSSS) algorithm for real-time magnetoencephalography (MEG) data processing. rSSS is based on the spatial signal space separation (SSS) method and it applies robust regression to automatically detect and remove bad MEG channels so that the results of SSS are not distorted. We extend the existing robust regression algorithm via three important new contributions: 1) a low-rank solver that efficiently performs matrix operations; 2) a subspace iteration scheme that selects bad MEG channels using low-order spherical harmonic functions; and 3) a parallel computing implementation that simultaneously runs multiple tasks to further speed up numerical computation.

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Salient areas in natural scenes are generally regarded as areas which the human eye will typically focus on, and finding these areas is the key step in object detection. In computer vision, many models have been proposed to simulate the behavior of eyes such as SaliencyToolBox (STB), Neuromorphic Vision Toolkit (NVT), and others, but they demand high computational cost and computing useful results mostly relies on their choice of parameters. Although some region-based approaches were proposed to reduce the computational complexity of feature maps, these approaches still were not able to work in real time.

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