Asia Pac J Sports Med Arthrosc Rehabil Technol
July 2024
The nature of aseptic prosthetic loosening mainly relates to the wear particles that induce inflammation and subsequent osteoclastogenesis. The ideal approach to impede wear particle-induced osteolysis should minimize inflammation and osteoclastogenesis. In this work, Co29Cr9W3Cu particles were used as a research model for the first time to explore the response of Co29Cr9W3Cu particles to inflammatory response and osteoclast activation in vitro and in vivo by using Co29Cr9W particles as the control group.
View Article and Find Full Text PDFSensors (Basel)
November 2022
Electrical impedance tomography (EIT) is a non-invasive detection technology that uses the electrical response value at the boundary of an observation field to image the conductivity changes in an area. When EIT is applied to the thoracic cavity of the human body, the conductivity change caused by the heartbeat will be concentrated in a sub-region of the thoracic cavity, that is, the heart region. In order to improve the spatial resolution of the target region, two sensor optimization methods based on conformal mapping theory were proposed in this study.
View Article and Find Full Text PDFInspired by the silkworm spinning process for production of tough cocoons, a gradient printing-assembly technique with silk fibroin (SF) and hydroxyapatite (HA) to achieve high strength scaffolds for bone regeneration is developed. A coaxial extrude-nozzle is employed to provide gathered thickening and shearing for aligned assembly. The aligned SF-HA assembles into the compacted nanostructure, which performs a maximum compressive strength of 166 MPa and bending strength of 40 MPa.
View Article and Find Full Text PDFBackground: Fascial autografts, which are easily available grafts, have provided a promising option in patients with massive rotator cuff tears. However, no fascial autografts other than the fascia lata have been reported, and the exact healing process of the fascia-to-bone interface is not well understood. The objective of this study is to histologically and biomechanically evaluate the effect of the thoracolumbar fascia (TLF) on fascia-to-bone healing.
View Article and Find Full Text PDFColloids Surf B Biointerfaces
December 2021
Polyether-ether-ketone (PEEK) materials have good biocompatibility, excellent corrosion resistance, chemical stability and an elastic modulus close to that of natural bone. However, due to its biological inertness, PEEK may affect osteogenic differentiation and leads to osseointegration failure, though PEEK is expected to improve osseointegration. In this work, by changing the power of femtosecond laser, micro-grooves are made on the PEEK surface.
View Article and Find Full Text PDFDesigning metal sulfides with unique configurations and exploring their electrochemical activities for hydrogen peroxide (HO) and hydrazine (NH) is challenging and desirable for various fields. Herein, hollow microflower-like CuS@C hybrids were successfully assembled and further exploited as a versatile electrochemical sensing platform for HO reduction and NH oxidation, of which the elaborate strategies make the perfect formation of hollow architecture, providing considerable electrocatalytic sites and fast charge transfer rate, while the appropriate introduction polydopamine-derived carbon skeleton facilitates the electronic conductivity and boosts structural robustness, thus generating wide linear range (0.05-14 and 0.
View Article and Find Full Text PDFZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
September 2020
Objective: To investigate the effects of three-dimensional (3D) printed Ti6Al4V-4Cu alloy on inflammation and osteogenic gene expression in mouse bone marrow mesenchymal stem cells (BMSCs) and mouse mononuclear macrophage line RAW264.7.
Methods: Ti6Al4V and Ti6Al4V-4Cu alloys were prepared by selective laser melting, and the extracts of the two materials were prepared according to the biological evaluation standard of medical devices.
Tendon injury repairs are big challenges in sports medicine, and fatty infiltration after tendon injury is very common and hampers tendon injury healing process. Tendon stem cells (TSCs), as precursors of tendon cells, have shown promising effect on injury tendon repair for their tenogenesis and tendon extracellular matrix formation. Adipocytes and lipids accumulation is a landmark event in pathological process of tendon injury, and this may induce tendon rupture in clinical practice.
View Article and Find Full Text PDFBackground: Chronic muscle injury is characteristics of fatty infiltration and fibrosis. Recently, fibro/adipogenic progenitors (FAPs) were found to be indispensable for muscular regeneration while were also responsible for fibrosis and fatty infiltration in muscle injury. Many myokines have been proven to regulate the adipose or cell proliferation.
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