Publications by authors named "Chenjing Tian"

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Dual Assay Validation of Rosmarinus officinalis Extract as an Inhibitor of SARS-CoV-2 Spike Protein: Combining Pseudovirus Testing, Yeast Two-Hybrid, and UPLC-Q Exactive Orbitrap-MS Profiling.

Yujing Huang Rufeng Luo Chenjing Tian Duntao Zu Jianni Yang

Phytochem Anal

November 2024

Article Synopsis

• This study investigates how Traditional Chinese Medicine (TCM) extracts can block the interaction of the SARS-CoV-2 Spike protein with the human ACE2 receptor, using advanced biochemical techniques.
• The research involved testing 91 different TCM extracts, finding that Rosmarinus officinalis (rosemary) was the most effective at preventing viral entry and disrupting the Spike-ACE2 interaction.
• The findings suggest that TCM extracts could be valuable in developing antiviral treatments, highlighting the potential of combining traditional methods with modern science.

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