Asperidulins A and B, two new prenylxanthone derivatives from an apple-derived fungus KIB-HACM-01.

Two new prenylxanthone derivatives, asperidulins A () and B (), along with a known emodin analogue () were isolated from an apple-derived fungus KIB-HACM-01. Their structures were elucidated by interpretation of HRMS, NMR, and comparisons of specific optical rotation. Asperidulin B () exhibited a moderate cytotoxicity against A549 and BEAS-2B with an IC values of 13.