Publications by authors named "Chenhu Gong"
Article Synopsis
- The study highlights that miR-875-5p is up-regulated in patients with non-small cell lung cancer (NSCLC) and promotes tumor cell growth and spread by inhibiting SATB2.
- CCK-8 assays indicate that introducing miR-875-5p mimics increases cell proliferation, while Transwell assays demonstrate enhanced invasion and migration of NSCLC cells.
- Luciferase and western blotting assays confirm that miR-875-5p directly interacts with SATB2's 3' UTR, reducing its protein expression, suggesting that targeting miR-875-5p could be a viable treatment strategy for NSCLC.
