Publications by authors named "Chengzhi Cong"

This study aimed to investigate the effect of traditional Chinese medicine (TCM) intervention on the risk of readmission and laboratory indicators in patients with rheumatoid arthritis hypercoagulable state. In the retrospective cohort design, patients with RA hospitalized between June 2013 and June 2021 at the First Affiliated Hospital of Anhui University of Chinese Medicine were followed up by telephone. Propensity score matching (PSM) was used to balance deviations in baseline information between patients in the hypercoagulable (HC) and non-hypercoagulable (Non-HC) groups, with exposure defined as receiving TCM treatment for ≥ 1 month.

View Article and Find Full Text PDF

Ethnopharmacological Relevance: Jianpi Qingre Chubi prescription primarily consists of a compound formula, also known as Huangqin Qingre Chubi Capsules (HQC), which strengthens the spleen and resolves dampness, clear heat, and collaterals. Long-term clinical use has shown that HQC improves joint swelling and pain in patients with osteoarthritis. Mechanistically, we demonstrated that HQC inhibits inflammatory responses, extracellular matrix degradation, and delays chondrocyte senescence.

View Article and Find Full Text PDF
Article Synopsis
  • - Ankylosing spondylitis (AS) is an autoimmune disease linked to inflammatory responses, often impacting the neutrophil to lymphocyte ratio (NLR), with recent research showing an increase in publications on this topic over the last two decades.
  • - This study uses bibliometric methods to analyze the trends, key players, and significant areas of research regarding NLR in AS, reviewing 1654 papers published between 2000 and 2023.
  • - Findings reveal that the U.S. leads in research output, with Harvard University being the most productive institution; the study emphasizes the importance of NLR as a potential biomarker for diagnosing and prognosing AS.
View Article and Find Full Text PDF

Ethnopharmacological Relevance: Huangqin Qingre Chubi Capsule (HQC) is a Chinese medicinal compound used for the treatment of damp-heat pattern rheumatism, guided by the traditional Chinese medicine syndrome differentiation practice. HQC has been used in the clinical treatment of rheumatic diseases for more than 20 years with remarkable efficacy. HQC has been experimentally shown to exert anti-arthritic effects via the Wnt signaling pathway.

View Article and Find Full Text PDF

Objective: The aim of this study was to investigate the relationship between Traditional Chinese medicine (TCM) and pain reduction, hospital readmission, and joint replacement in patients with osteoarthritis (OA). Chinese herbal medicine (CHM) prescription patterns were further analyzed to confirm the association with prognosis and quality of life in OA patients.

Methods: We retrospectively followed 3,850 hospitalized patients with osteoarthritis between January 2018 and December 2022 using the hospital's HIS system.

View Article and Find Full Text PDF

Objective: This study aimed to evaluate the effect of traditional Chinese medicine (TCM) on endpoint events in patients with gouty arthritis (GA).

Methods And Materials: A total of 2091 hospitalized GA patients were followed up by telephone, and propensity score matching (PSM) was used to reduce potential bias in the study design. Cox proportional risk model and Kaplan-Meier survival curve were utilized to analyze the impact and time effect of factors on the readmission of GA patients.

View Article and Find Full Text PDF

This study aimed to analyze the impact of traditional Chinese medicine(TCM) on the risk of re-admission for ankylosing spondylitis(AS) patients with dampness-heat syndrome. In this study, a telephone follow-up was conducted on 1 295 AS inpatients, and after screening and exclusions, 1 044 successfully followed-up patients were included. A retrospective cohort study was conducted using propensity score matching(PSM), and a Cox proportional risk model was employed to assess the effect of various factors on the risk of re-admission for AS patients with dampness-heat syndrome.

View Article and Find Full Text PDF

Since the incidence of gouty arthritis (GA) exhibits yearly increases, accurate assessment and early treatment have significant values for improving disease conditions and monitoring prognosis. Neutrophil to lymphocyte ratio (NLR) is a common indicator in blood routine, which has the characteristics of easy access and low cost. In recent years, NLR has been proven to be an effective indicator for guiding the diagnosis, treatment, and prognosis of various diseases.

View Article and Find Full Text PDF