Homologous recombination deficiency score is an independent prognostic factor in esophageal squamous cell carcinoma.

Homologous recombination deficiency (HRD) represents an impairment in the homologous recombination repair (HRR) pathway, crucial for repairing DNA double-strand breaks and contributing to genomic instability in cancer. The HRD score may be a more reliable biomarker than HRR-related gene mutations for identifying patients sensitive to poly(ADP-ribose) polymerase inhibitors. Despite its relevance in various cancers, the HRD score remains underexplored in esophageal squamous cell carcinoma (ESCC).

Efficient Integration of Neural Representations for Dynamic Humans.

While numerous studies have explored NeRF-based novel view synthesis for dynamic humans, they often require training that exceeds several hours, limiting their practicality. Efforts to improve training efficiency have also encountered challenges because it is hard to optimize non-rigid transformations, thus leading to coarse renderings. In this work, we introduce an innovative approach for efficiently learning and integrating neural human representations.

Erosion Attack: Harnessing Corruption To Improve Adversarial Examples.

Although adversarial examples pose a serious threat to deep neural networks, most transferable adversarial attacks are ineffective against black-box defense models. This may lead to the mistaken belief that adversarial examples are not truly threatening. In this paper, we propose a novel transferable attack that can defeat a wide range of black-box defenses and highlight their security limitations.

DEFEAT: Decoupled feature attack across deep neural networks.

Adversarial attacks pose a security challenge for deep neural networks, motivating researchers to build various defense methods. Consequently, the performance of black-box attacks turns down under defense scenarios. A significant observation is that some feature-level attacks achieve an excellent success rate to fool undefended models, while their transferability is severely degraded when encountering defenses, which give a false sense of security.

MiR-506-3p suppresses the proliferation of ovarian cancer cells by negatively regulating the expression of MTMR6.

MicroRNAs have been reported to play a crucial role in ovarian cancer (OC) as the most lethal malignancy of the women. Here, we found miR-506-3p was significantly down-regulated in OC tissues compared with corresponding adjacent nontumor tissues. Ectopic miR-506-3p expression inhibited OC cell growth and proliferation using MTT and colony formation assay.

Effect of biomedical organic compounds on the setting reaction of calcium phosphates.

In the present study, the effect of biomedical organic compounds (starch, sodium alginate, chitosan and gelatin) on the hydration of calcium phosphates was studied using X-ray diffraction, infrared spectroscopy, scanning electron microscopy and XPS analysis. Amorphous calcium phosphate (ACP) was prepared by a mechanochemical route and mixed with biomedical organic compounds. A solidification reaction occurred between ACP and dicalcium phosphate dihydrate (DCPD); the hydration product was poorly crystallized hydroxyapatite (HA).