Publications by authors named "Chenguang Zhan"

Osteoporosis is a prevalent skeletal condition characterized by reduced bone mass and strength, leading to increased fragility. Buqi-Tongluo (BQTL) decoction, a traditional Chinese medicine (TCM) prescription, has yet to be fully evaluated for its potential in treating bone diseases such as osteoporosis. To investigate the mechanism by which BQTL decoction inhibits osteoclast differentiation in vitro and validate these findings through in vivo experiments.

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Background: To investigate the clinical outcomes of percutaneous vertebroplasty (PVP) versus percutaneous vertebroplasty combined with pediculoplasty (PVP-PP) for Kümmell's disease (KD).

Methods: Between February 2017 and November 2020, 76 patients with KD undergoing PVP or PVP-PP were included in this retrospective study. Based on the PVP whether combined with pediculoplasty, those patients were divided into PVP group (n = 39) and PVP-PP group (n = 37).

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Article Synopsis
  • - The study evaluates surgical strategies for treating cervical ossification of the posterior longitudinal ligament (OPLL) specifically in the C segment, discussing various surgical methods.
  • - Different surgical options include laminectomy for multiple segments, canal-expansive laminoplasty for specific cases, and the Shelter technique for severe encroachment, each with unique pros and cons such as mobility loss, complication risks, and effectiveness.
  • - The authors conclude that while posterior surgery is the main approach for C segment OPLL, its complexity and limited long-term effectiveness due to progressive ossification necessitate further research.
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  • * PMMA-PS group experienced longer operation times and higher hospitalization costs, but both groups showed similar improvements in pain and disability scores post-surgery, with high fusion rates of 100% for PMMA-PS and 96.15% for CPS.
  • * The findings suggest that while PMMA-PS showed no significant benefits in screw stability or overall outcomes compared to CPS, the routine use of PMMA-PS in such cases is not recommended due
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