The nitrogen removal performance and biological mechanism of Platymonas helgolandica var. Tsingtaoensis (P. helgolandica) were investigated in treating mariculture wastewater under different light: dark (L:D) photoperiods.
View Article and Find Full Text PDFSocial media rumors have the capacity to harm the public perception and the social progress. The news propagation pattern is a key clue for detecting rumors. Existing propagation-based rumor detection methods represent propagation patterns as a static graph structure.
View Article and Find Full Text PDFWater quality prediction is the basis for the prevention and control of water pollution. In this paper, to address the problem of low prediction accuracy of existing empirical models due to the non-smoothness and nonlinearity of water quality series, a novel water quality forecasting model integrating synchrosqueezed wavelet transform and deep extreme learning machine optimized with the sparrow search algorithm (SWT-SSA-DELM) was proposed. First, the water quality series was denoised by SWT to reduce the non-stationarity and randomness of water quality series.
View Article and Find Full Text PDFThis paper presents a micro-electro-mechanical systems (MEMS) processing technology for Aluminum Nitride (AlN) Lamb-wave resonators (LWRs). Two LWRs with different frequencies of 402.1 MHz and 2.
View Article and Find Full Text PDFThe differences of cultured organism species, aquaculture model and supervisor mode lead to different carbon/nitrogen ratios in mariculture wastewater. Therefore, the performance, microbial community and enzymatic activity of sequencing batch biofilm reactor were compared in treating synthetic mariculture wastewater at different chemical oxygen demand/nitrogen (COD/N) ratios. Compared with COD/N ratio of 6, the ammonia-oxidizing rate and nitrite-oxidizing rate at COD/N ratio of 5, 4 and 3 increased by 3.
View Article and Find Full Text PDFAccurate and reliable water quality forecasting is of great significance for water resource optimization and management. This study focuses on the prediction of water quality parameters such as the dissolved oxygen (DO) in a river system. The accuracy of traditional water quality prediction methods is generally low, and the prediction results have serious autocorrelation.
View Article and Find Full Text PDFTarget identification is important for drug discovery. Unfortunately, no drug targets have been found in Ichthyophthirius multifiliis until now and further limited development of the novel drug for Ichthyophthiriasis. In this study, an iTRAQ-based quantitative proteomic analysis was used to find the target of malachite green (MG), exhibiting greater efficacy than the existing drugs, against I.
View Article and Find Full Text PDFThe freeze-thaw cycle is one of the important factors in inducing a dam-break in the permafrost region, so it is of great practical significance to study the mechanism of the failure deformation of tailings dams under freeze-thaw cycles. In this paper, the water-heat-force coupling model of a tailings dam considering frost-thaw damage is established, and the freeze-thaw cyclic ageing deformation of a tailings dam in a seasonally frozen soil area is studied. The correctness of the model is validated by numerical calculation.
View Article and Find Full Text PDFThe role of long non-coding RNA (lncRNA) in idiopathic pulmonary fibrosis (IPF) is poorly understood. We found a novel lncRNA-ITPF that was upregulated in IPF. Bioinformatics and in vitro translation verified that lncITPF is an actual lncRNA, and its conservation is in evolution.
View Article and Find Full Text PDFToxicol Appl Pharmacol
October 2018
Pulmonary fibrosis is a progressive disorder with poor prognosis and limited treatment options. Therefore, novel therapeutic drugs should be developed in preclinical studies. In this study, we designed and synthesized a novel compound named formononetin-7-sal ester (FS).
View Article and Find Full Text PDFBackground And Objective: The nature of pulmonary fibrosis involves inadequate repair of the epithelial cell barrier accompanied by impaired regulation of the fibroblast. Moreover, pulmonary fibrosis currently lacks an effective therapeutic drug. This study targets the protection of the epithelial cell and fibroblast to identify a novel, potentially therapeutic drug (i.
View Article and Find Full Text PDFDexamethasone, a known immunosuppressant, can inhibit the immune response and increase the amount of pathogen in body, but the role of dexamethasone affecting susceptibility of crucian carp (Carassius auratus) to pathogen is unclear. The effects of dexamethasone on susceptibility of crucian carp to Aeromonas hydrophila were investigated in this study. The fish were divided into four groups randomly and injected intraperitoneally by dexamethasone for 0 day (group D), 3 days (group C), 6 days (group B), and 9 days (group A), respectively.
View Article and Find Full Text PDFSince the use of malachite green was banned, it is desirable to search for alternative drug to control Ichthyophthirius multifiliis infection. Moreover, route of administration which is easy to implement and less stressful to fish is important to treat infection of fish with this parasite. It is also important to enhance protective effect against Aeromonas hydrophila infection after parasitism by I.
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