Publications by authors named "Chengtao Niu"
Article Synopsis
- Clear cell renal cell carcinoma (ccRCC) has a high incidence and mortality rate, and current treatments yield poor prognostic outcomes for patients.
- *Recent research highlights the potential of methylation modifications as molecular targets in ccRCC, identifying 57 methylation-related genes (MRGs) using data from large cancer databases.
- *A Methylation-Related Risk Score (MARS) was developed, which showed significant prognostic value and the ability to predict immune responses and treatment outcomes in ccRCC patients, aiding in more personalized treatment strategies.
Background: Clear cell renal cell carcinoma (ccRCC), the most common pathological subtype of kidney cancer, accounts for approximately 70% to 80% of all cases. Histone deacetylase 10 (HDAC10) belongs to the HDAC class IIb subgroup, one of the histone deacetylases (HDAC) family. Previous studies suggest that HDAC10 may regulate the development of multiple tumor types.
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