Publications by authors named "Chengtao Mao"
Article Synopsis
- Limited access to hematopoietic stem cells (HSCs) hampers the broader application of HSC therapies, necessitating better methods for their expansion.
- The study introduces a biomimetic Microniche system that effectively expands HSCs, particularly those favoring the creation of megakaryocytes, and showcases successful implementation in a stirred bioreactor.
- Key findings reveal that the productive megakaryocyte-biased HSCs can be identified within a specific subpopulation, and the advancement in HSC expansion is attributed to an optimized microenvironment that provides essential cytokines and physical support.
