Progress of Angiogenesis Signal Pathway and Antiangiogenic Drugs in Nasopharyngeal Carcinoma.

Nasopharyngeal cancer is a rare cancer with unique ethnic and geographic distribution. Since nasopharyngeal cancer often originates from the pharyngeal crypt, early symptoms are not obvious. They are difficult to detect in time, and the disease is usually diagnosed and treated only when it has progressed to an advanced-stage.

Homolytic H dissociation for enhanced hydrogenation catalysis on oxides.

The limited surface coverage and activity of active hydrides on oxide surfaces pose challenges for efficient hydrogenation reactions. Herein, we quantitatively distinguish the long-puzzling homolytic dissociation of hydrogen from the heterolytic pathway on GaO, that is useful for enhancing hydrogenation ability of oxides. By combining transient kinetic analysis with infrared and mass spectroscopies, we identify the catalytic role of coordinatively unsaturated Ga in homolytic H dissociation, which is formed in-situ during the initial heterolytic dissociation.

Fast-Response Nickel-Promoted Indium Oxide Catalysts for Carbon Dioxide Hydrogenation from Intermittent Solar Hydrogen.

Construction of a "net-zero-emission" system through CO hydrogenation to methanol with solar energy is an eco-friendly way to mitigate the greenhouse effect. Traditional CO hydrogenation demands centralized mass production for cost reduction with mass water electrolysis for hydrogen supply. To achieve continuous reaction with intermittent and fluctuating flow of H on a small-scale for distributed application scenarios, modulating the catalyst interface environment and chemical adsorption capacity to adapt fluctuating reaction conditions is highly desired.

Nature of Catalytic Behavior of Cobalt Oxides for CO Hydrogenation.

Cobalt oxide (CoO ) catalysts are widely applied in CO hydrogenation but suffer from structural evolution during the reaction. This paper describes the complicated structure-performance relationship under reaction conditions. An iterative approach was employed to simulate the reduction process with the help of neural network potential-accelerated molecular dynamics.

Identification of From the Skin Ulcer Disease of Crocodile Lizards () and Probiotics as the Control Measure.

The crocodile lizard () is an endangered ancient reptile species. Captive breeding is an important conservation measure for the potential restoration and recovery of their wild populations. However, a skin ulcer disease caused by an unknown pathogen has become a serious threat to captive breeding individuals.

Moderate Surface Segregation Promotes Selective Ethanol Production in CO Hydrogenation Reaction over CoCu Catalysts.

Cobalt-copper (CoCu) catalysts have industrial potential in CO/CO hydrogenation reactions, and CoCu alloy has been elucidated as a major active phase during reactions. However, due to elemental surface segregation and dealloying phenomena, the actual surface morphology of CoCu alloy is still unclear. Combining theory and experiment, the dual effect of surface segregation and varied CO coverage over the CoCu(111) surface on the reactivity in CO hydrogenation reactions is explored.

Correlation study of cytokine levels in alveolar lavage fluid with exhaled nitric oxide and lung function in children with bronchial asthma.

Background: The associations between cytokines in the bronchoalveolar lavage fluid (BALF), lung cytokine expression, fractional exhaled nitric oxide (FeNO) and pulmonary function test results in pediatric asthmatics have not been extensively characterized. This study sought to explore correlations between cytokines BALF, FeNO, and pulmonary function test results.

Methods: From October 2018 to October 2020, a prospective study was conducted on 42 children with asthma and 17 children with pulmonary foreign bodies that required bronchoscopy.

Strong Electronic Oxide-Support Interaction over InO/ZrO for Highly Selective CO Hydrogenation to Methanol.

Metal oxides are widely employed in heterogeneous catalysis, but it remains challenging to determine their exact structure and understand the reaction mechanisms at the molecular level due to their structural complexity, in particular for binary oxides. This paper describes the observation of the strong electronic interaction between InO and monoclinic ZrO (m-ZrO) by XPS experiments combined with theoretical studies, which leads to support-dependent methanol selectivity. InO/m-ZrO exhibits methanol selectivity up to 84.

The Interplay between Structure and Product Selectivity of CO Hydrogenation.

Identification of the active structure under reaction conditions is of great importance for the rational design of heterogeneous catalysts. However, this is often hampered by their structural complexity. The interplay between the surface structure of Co O and the CO hydrogenation is described.

Activation and Spillover of Hydrogen on Sub-1 nm Palladium Nanoclusters Confined within Sodalite Zeolite for the Semi-Hydrogenation of Alkynes.

The search for efficient nontoxic catalysts able to perform industrial hydrogenations is a topic of interest, with relevance to many catalytic processes. Herein, we describe a mechanistic phenomenon for the activation and spillover of hydrogen for remarkable selectivity in the semi-hydrogenation of acetylene over sub-1 nm Pd nanoclusters confined within sodalite (SOD) zeolite (Pd@SOD). Specifically, hydrogen is dissociated on the Pd nanoclusters to form hydrogen species (i.

pH- and GSH-Sensitive Hyaluronic Acid-MP Conjugate Micelles for Intracellular Delivery of Doxorubicin to Colon Cancer Cells and Cancer Stem Cells.

A dual-sensitive polymeric drug conjugate (HA-SS-MP) was synthesized by conjugating hydrophobic 6-mercaptopurine (MP) to thiolated hyaluronic acid (HA) as the carrier and ligand to deliver doxorubicin (Dox) to parental colon cancer and colon cancer stem cells. Because of the amphiphilic nature of HA-SS-MP, it was self-assembled in the aqueous media, and Dox was physically encapsulated in the core of the micelles. The particle size and the zeta potential of the micelle were analyzed by dynamic light scattering (DLS), and the morphology of the micelle was investigated using transmission electron microscopy (TEM).