Publications by authors named "Chengqi Zhao"
Article Synopsis
- Chronic migraine (CM) greatly affects both physical and mental health, prompting a network meta-analysis (NMA) to evaluate the effectiveness and safety of various prophylactic drugs for CM.
- The study analyzed 24 randomized controlled trials (RCTs) with 8,789 patients, finding that Botulinum toxin A had the most significant reduction in monthly migraine days, while Topiramate was best for achieving a 50% reduction in frequency.
- The results suggested that Botulinum toxin A is the most effective and safe option, with CGRP monoclonal antibodies closely following in both efficacy and safety.
A novel electrochemical chiral sensor has been designed based on the principle of competitive host-guest interaction and utilized for the discrimination of electroinactive proline (Pro) isomers. Electroactive methylene blue (MB) was used as the signal probe, which was combined with multi-walled carbon nanotubes (MWCNTs)-decorated β-cyclodextrin (β-CD), host-guest interaction, where the oxidation peak currents of MB decreased after isomers of Pro were combined with the MWCNTs-β-CD a competitive host-guest interaction. Due to the steric configuration of L-Pro matching the cavity of β-CD, more L-Pro than D-Pro was combined with MWCNTs-β-CD, resulting in a more pronounced decrease of MB peak currents.
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