[Immunological characteristics of patients with anti-synthetase syndrome overlap with rheumatoid arthritis].

Objective: To investigate the clinical and immunological characteristics of anti-synthetase syndrome (ASS) patients overlap with rheumatoid arthritis (RA).

Methods: A retrospective analysis was conducted on ASS patients with arthritis who were treated at Peking University People' s Hospital. Data collected included demographic information, clinical manifestations, laboratory features, lymphocyte subsets in peripheral blood, and treatments.

A cadaveric study showing the OLIF corridor dimensions after retraction of the abdominal great arteries and psoas major.

The aim of this study is to assess the oblique lateral interbody fusion (OLIF) corridor dimensions when the abdominal great arteries (the abdominal aorta or common iliac arteries) and psoas major are retracted. Twenty embalmed cadaveric specimens were dissected. The widths of the OLIF operative corridor at L1-2, L2-3, L3-4, and L4-5 were measured with the psoas major and abdominal great arteries in static state, with psoas retraction, and with mild retraction of the abdominal great arteries.

Single-nucleus transcriptome unveils the role of ferroptosis in ischemic stroke.

Multiple cell death pathways are involved in neuronal death in ischemic stroke (IS). However, the role of different cell death pathways in different cell types has not been elucidated. By analyzing three single-nucleus RNA sequencing (snRNA-seq) data of IS, we first found that a variety of programmed cell death (PCD) -related genes were significantly changed in different cell types.

Quantitative analysis of low-content impurity crystal forms in canagliflozin tablets by NIR solid-state analysis technique.

Canagliflozin (CFZ) tablets was a commercially new class of anti-diabetic drug, CFZ had various anhydrate crystal forms and two hydrate crystal forms (Canagliflozin hemihydrate (Hemi-CFZ) and Canagliflozin monohydrate (Mono-CFZ) crystal form). The active pharmaceutical ingredients (APIs) of commercially available CFZ tablets were Hemi-CFZ, was easily convert to CFZ or Mono-CFZ under the influence of temperature, pressure, humidity and other factors in tablets processing, storage, and transportation, thus affected bioavailability and efficacy of tablets. Therefore, quantitative analysis of low-content CFZ and Mono-CFZ in tablets was essential to control tablets' quality.

Transition Metal Functionalized CNS as High-Performance Trifunctional Catalysts with Integrated Descriptors toward Hydrogen Evolution, Oxygen Evolution, and Oxygen Reduction Reactions: A Case of High-Throughput First-Principles Screening within the Framework of TM-N@CNS.

In energy conversion and storage technologies, the design of highly efficient trifunctional electrocatalysts integrating with the high hydrogen evolution reaction (HER) and oxygen evolution/reduction reaction (OER/ORR) activities is highly desirable. Herein, utilizing first-principles computations, a novel periodically ordered macropore CNS monolayer was proposed, and the stability analysis attests to its good stability. Single transition metal (TM) atom anchored onto this newly proposed CNS monolayer to form single-atom catalysts, as achieved by TM-N@CNS, among which the Co-N@CNS is the most promising multifunctional catalyst toward HER/OER/ORR with low overpotential of 0.

Adsorption of lithium ions from aqueous solution by magnetic aluminum-based adsorbents.

Magnetic aluminum-based adsorbents (MLDHs) were prepared with a coprecipitation method and used to separate lithium ions from the aqueous solutions. In static adsorption experiment, the adsorption capacity of MLDHs for lithium ions reached 8.22 mg/g.

Zero-Strain Na V (PO ) F @Rgo/CNT Composite as a Wide-Temperature-Tolerance Cathode for Na-Ion Batteries with Ultrahigh-Rate Performance.

Sodium-ion batteries (SIBs) are widely considered a hopeful alternative to lithium-ion battery technology. However, they still face challenges, such as low rate capability, unsatisfactory cycling stability, and inferior variable-temperature performance. In this study, a hierarchical Na V (PO ) F (NVPF) @reduced graphene oxide (rGO)/carbon nanotube (CNT) composite (NVPF@rGO/CNT) is successfully constructed.

Kagome-like BiP Monolayer: An Emerging Quasi-Direct Auxetic Semiconductor Coupled with High Anisotropic Mobility toward Visible-Light-Driven Photoelectrocatalytic pH-Robust Overall Water-Splitting.

Two-dimensional (2D) Janus materials exhibit an outstanding potential that can meet the rigorous requirements of photocatalytic water splitting resulting from their unique atomic arrangement. However, these materials are quite scarce. Through ab initio density functional theory calculations, we introduce a kagome topology into the honeycomb lattice of blue phosphorene using phosphorus and bismuth atoms to build a hybrid honeycomb-like kagome lattice, realized by a hitherto unknown kagome-like Janus-like BiP monolayer with robust stability.

Structural design and performance study of primitive triply periodic minimal surfaces Ti6Al4V biomimetic scaffold.

This paper comprehensively evaluated the static mechanical compressive properties, permeability, and cell adhesion effect on the inner wall of the Primitive triply periodic minimal surface Ti6Al4V bionic scaffolds with different axial diameter ratios through numerical simulation and experiments. The results show that when the axial diameter ratio is 1:2, the elastic modulus of the scaffold is about 1.25 and the yield strength is about 1.

Evaluation of antibiotic combination of Litsea cubeba essential oil on Vibrio parahaemolyticus inhibition mechanism and anti-biofilm ability.

Vibrio parahaemolyticus (V. parahaemolyticus) is a common pathogen in seafood. The use of antibiotics is a primary tool to prevent and control V.

Degradation of internal fixation materials based on antibacterial and absorbable silk containing different gentamicin concentrations.

Adding gentamicin to silk fibroin enhances both the antibacterial performance and degradation rate of silk-based materials. The increased material degradation rate can affect the strength of early internal fixation, resulting in internal fixation failure. This study sought to adjust the gentamicin concentration to control the material degradation rate, thereby better meeting clinical application requirements.

Mesoporous vanadium nitride as anion storage electrode for reverse dual-ion hybrid supercapacitor.

In traditional dual-ion systems, the cathode usually is employed as anion-storage materials. Herein, we propose a new dual-ion hybrid supercapacitor with reverse anion/cation-storage mechanism, consisting of a mesoporous (MPs) VN anode as a pivotal anion-storage material and KMnO nanosheet arrays grown on carbon cloth (NSs/CC) as (K-storage) cathode. During charge/discharge, the anode and cathode reversibly store/release OH ions and K ions, respectively.

Multifunctional integrated VN/VO heterostructure sulfur hosts for advanced lithium-sulfur batteries.

Lithium-sulfur (Li-S) batteries show great potential in future electric transportation and large-scale grid storage applications because of their attractive theoretical energy density (2600 W h kg) and relatively abundant sulfur reserves. However, the rapid capacity decay and unsatisfactory sulfur loading caused by the lithium polysulphide (LiPS) dissolution and low electrical conductivity of sulfur are the most urgent issues plaguing its practical applications. Herein, we report a multifunctional nanoporous (NP) VN/VO binary host that can efficiently resolve the above conflicts by the synergy between the functions of two materials.

Surgical safe zones for oblique lumbar interbody fusion of L1-5: A cadaveric study.

To evaluate the operating range and morphology of the surgical safe zone for oblique lumbar interbody fusion (OLIF). Twenty embalmed full-torso cadaveric specimens were dissected. The oblique corridor and the distance between adjacent lumbar arteries were measured in a static state and with psoas major retraction.

A new potassium dual-ion hybrid supercapacitor based on battery-type Ni(OH) nanotube arrays and pseudocapacitor-type VO-anchored carbon nanotubes electrodes.

Hybrid supercapacitors (HSCs) with the characteristics of high energy density, long cycle life and without altering their power density need to be developed urgently. Herein, a novel dual-ion hybrid supercapacitors (DHSCs) with Ni(OH) nanotube arrays (NTAs) as positive electrode and VO directly grown on freestanding carbon nanotubes (CNTs) as negative electrode is assembled. In charging mechanism of DHSCs, K are inserted into the VO negative while OH react with Ni(OH) positive; during discharge, the K and OH are released from VO negative and Ni(OH) positive, respectively, and return back to the electrolyte, which is quite different from traditional metal ion or alkaline supercapacitors.

Semi-coherent cation-rich Mn-Cu oxides heterostructures as cathode for novel aqueous potassium dual-ion energy storage devices.

In this work, combining both advantages of aqueous energy storage systems (ESS) and conventional dual-ion ESS, a novel aqueous dual-ion ESS is developed based on K and OH electrochemistry by employing semi-coherent KMnO-CuO (sc-Mn-Cu) cathode. Profting from the elaborate design, the electrolyte and cathode simultaneously act as source of cations. In the novel aqueous dual-ion ESS configuration, the dependence of the performance on the electrolyte salt concentration is reduced and the sc-Mn-Cu cathode can host OH with lower working potentials by conversion mechanism.

Geological significance of new zircon U-Pb geochronology and geochemistry: Niuxinshan intrusive complex, northern North China Craton.

The Huajian gold deposit is one of the largest hydrothermal intrusion-related gold deposits in eastern Hebei Province, located in the northern margin of the North China Craton (NCC). The mineralization in this district displays a close spatial association with the shoshonitic Niuxinshan intrusive complex (NIC), which contributes to the characterization of the metallogeny associated with convergent margin magmatism. In the current study, new geochronological and geochemical data are combined with previously published isotopic data, obtained from the granitic rocks in the NIC, to constrain the timing of the district's tectonic setting transformation and determine its bearing on regional metallogeny.

Radiation Exposure Reduction in Ultrasound-Guided Transforaminal Percutaneous Endoscopic Lumbar Discectomy for Lumbar Disc Herniation: A Randomized Controlled Trial.

Background: Transforaminal percutaneous endoscopic lumbar discectomy (TF-PELD) is a minimally invasive technique with high radiation exposure. The purpose of this study was to compare radiation exposure of ultrasound-guided TF-PELD with fluoroscopy-guided TF-PELD.

Methods: In this prospective randomized controlled clinical trial, 60 patients with lumbar disc herniation were enrolled and randomly assigned to 2 groups (30 cases in each group): the ultrasound-guided group or the fluoroscopy-guided group.

Immunohistochemical detection of E7 human papillomavirus protein in pre‑malignant and malignant lesions of the uterine cervix.

Human papillomavirus (HPV) E7 protein expression is caused by HPV viral DNA integration into human cellular DNA, and is a prerequisite for the development and progression of cervical cancer. The present study aimed to evaluate the role of E7 protein as a biomarker for identification of transformed cervical epithelial cells during the early stages of cervical cancer. Specific monoclonal antibodies to the E7 protein of high‑risk HPVs were generated and characterized for applications in immunocytochemistry and immunohistochemistry using cervical epithelial cells or biopsy tissue slides.

Surgical Outcome and Prognostic Analysis of Transoral Atlantoaxial Reduction Plate System for Basilar Invagination: A Voxel-Based Morphometry Study.

Background: The use of a transoral atlantoaxial reduction plate (TARP) system is an effective surgical approach for the treatment of basilar invagination. With the aim of improving the therapeutic efficacy of the TARP operation, we conducted a voxel-based morphometric study to quantitatively investigate the descent of the odontoid process and craniocervical volume changes.

Methods: We enrolled 20 patients with basilar invagination who underwent a TARP procedure.

An antibacterial and absorbable silk-based fixation material with impressive mechanical properties and biocompatibility.

Implant-associated infections and non-absorbing materials are two important reasons for a second surgical procedure to remove internal fixation devices after an orthopedic internal fixation surgery. The objective of this study was to produce an antibacterial and absorbable fixation screw by adding gentamicin to silk-based materials. The antibacterial activity was assessed against Staphylococcus aureus (S.

Treatment of Basilar Invagination With Klippel-Feil Syndrome: Atlantoaxial Joint Distraction and Fixation With Transoral Atlantoaxial Reduction Plate.

Background: Klippel-Feil syndrome (KFS) is characterized by congenital vertebral fusion of the cervical spine and a wide spectrum of associated anomalies. In patients with KFS with basilar invagination (BI), compression of the brainstem and upper cervical cord results in neurological deficits, and decompression and occipitocervical reconstruction are required. The highly varied anatomy of KFS makes a posterior occipitocervical fixation strategy challenging.