Publications by authors named "Chenglei Zhang"

Article Synopsis
  • * The study investigates terazosin, a drug identified through screening, to see how it improves β-cell function by activating the MST1-Foxo3a pathway and promoting mitophagy.
  • * Results show terazosin enhances insulin secretion and overall pancreatic health in NAFPD mice by restoring mitochondrial function and inhibiting a harmful signaling pathway, making it a potential treatment for patients with NAFPD and hypertension.
View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the PMTCT (Prevention of Mother-to-Child Transmission) model combined with Health Management Teams (HMT) to reduce adverse outcomes in pregnant women with syphilis in the Ningxia region.
  • Findings show that this model improved participants' knowledge and counseling rates, leading to a significant decrease in adverse pregnancy outcomes like miscarriages and preterm births.
  • The study also highlights factors linked to negative outcomes, such as non-residency, unmarried status, and lower education levels, emphasizing the need for equitable healthcare for vulnerable populations in Ningxia.
View Article and Find Full Text PDF
Article Synopsis
  • The study looks at male breast cancer (MBC) in China, which isn't very common, to see how it affects patients there.
  • Researchers collected information from 1,119 MBC patients and found that the average age when they were diagnosed was about 61 years old, with most patients having surgery to remove the tumor.
  • The results showed that certain treatments, like taxane-based medicines, help patients live longer, but more research is needed to understand MBC in China better.
View Article and Find Full Text PDF

Background: Hepatitis B mother-to-child transmission interruption (PMTCT) poses a formidable challenge in underdeveloped regions of China. This study aims to evaluate the effectiveness of PMTCT and the health management team (HMT) model in Ningxia, China, as well as the risk factors for adverse outcomes.

Methods: The PMTCT + HMT model was established, and 360 pregnant women diagnosed with HBV infection in 2020-2022 were selected and divided into the control and the study groups based on different intervention modes.

View Article and Find Full Text PDF

This study aims to investigate the effects of 1,25-dihydroxyvitamin D3 (1,25(OH)VitD) on osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) and the activity of hPDLSC sheets and the differences in the tissue regeneration activity of hPDLSC sheets on tooth root fragment treated by different methods. Healthy caries-free premolars were collected. The hPDLSCs were obtained by enzymatic digestion.

View Article and Find Full Text PDF

Periodontitis is a chronic inflammatory disease caused by Porphyromonas gingivalis and other bacteria, and human periodontal ligament stem cells (hPDLSCs) are a promising candidate for the treatment of periodontal supporting tissue defects. This study aimed to investigate the effect of 1α,25-dihydroxyvitamin D [1,25(OH)VitD] on osteogenic differentiation of hPDLSCs in an in vitro periodontitis model and whether it can improve inflammatory status. hPDLSCs were in vitro isolated and identified.

View Article and Find Full Text PDF

Objective: This study aims to establish a radiomics-based machine learning model that predicts the risk of transient ischemic attack in patients with mild carotid stenosis (30-50% North American Symptomatic Carotid Endarterectomy Trial) using extracted computed tomography radiomics features and clinical information.

Methods: A total of 179 patients underwent carotid computed tomography angiography (CTA), and 219 carotid arteries with a plaque at the carotid bifurcation or proximal to the internal carotid artery were selected. The patients were divided into two groups; patients with symptoms of transient ischemic attack after CTA and patients without symptoms of transient ischemic attack after CTA.

View Article and Find Full Text PDF

Based on the data from the 2012-2018 China Family Panel Survey, this study examines the impact of household wealth on individuals' mental health using a two-way fixed effects model. The findings indicate that household wealth exerts a significant positive effect on individuals' mental health. Furthermore, this study shows that the impact of household wealth on individuals' mental health is nonlinear but inverted U-shaped.

View Article and Find Full Text PDF

In order to reduce the cost of manufacturing and service for the Cloud 3D printing (C3DP) manufacturing grid, to solve the problem of resources optimization deployment for no-need preference under circumstance of cloud manufacturing, consider the interests of enterprises which need Cloud 3D printing resources and cloud platform operators, together with QoS and flexibility of both sides in the process of Cloud 3D printing resources configuration service, a task-service network node matching method based on Multi-Objective optimization model in dynamic hyper-network environment is built for resource allocation. This model represents interests of the above-mentioned two parties. In addition, the model examples are solved by modifying Mathematical algorithm of Node Matching and Evolutionary Solutions.

View Article and Find Full Text PDF

Nonalcoholic fatty pancreas disease (NAFPD) is an emerging disease that has gained an increasing amount of attention in recent years. It describes fat accumulation in the pancreas with insignificant alcohol consumption, but the pathogenesis is largely unknown. A wide range of terms have been used to describe the phenomenon of pancreatic fat accumulation, but NAFPD remains an under-recognized and non-independent disorder.

View Article and Find Full Text PDF

Focusing on service control factors, rapid changes in manufacturing environments, the difficulty of resource allocation evaluation, resource optimization for 3D printing services (3DPSs) in cloud manufacturing environments, and so on, an indicator evaluation framework is proposed for the cloud 3D printing (C3DP) order task execution process based on a Pareto optimal set algorithm that is optimized and evaluated for remotely distributed 3D printing equipment resources. Combined with the multi-objective method of data normalization, an optimization model for C3DP order execution based on the Pareto optimal set algorithm is constructed with these agents' dynamic autonomy and distributed processing. This model can perform functions such as automatic matching and optimization of candidate services, and it is dynamic and reliable in the C3DP order task execution process based on the Pareto optimal set algorithm.

View Article and Find Full Text PDF

Background: In Chinese culture, smoking can promote social connectedness and integration. We therefore hypothesized that smoking would be negatively associated with loneliness in China. Given that loneliness is common and associated with adverse academic and health outcomes in university freshmen, examining correlates of loneliness in this population may deepen our understanding on the etiology of loneliness.

View Article and Find Full Text PDF

Background: We present the expression of miR-146a in abdominal aortic aneurysms (AAA) patients, and its mechanism for regulating inflammation and development in AAA patients.

Methods: The expression of miR-146a in serum, PBMC, and abdominal aorta tissues was measured in AAA patients.

Results: We found that level of miR-146a in the serum and its expression in AAA tissues were significantly higher than that in healthy people or normal abdominal aorta tissues.

View Article and Find Full Text PDF

With the rapid development of photovoltaic industry, the recycling of waste solar photovoltaic (PV) panels is becoming a critical and global challenge. Considering PV panels recycling is significantly effective and worthwhile to save natural resources and reduce the cost of production, how to selectively recycle valuable components of PV panels is the hot and dominant topic. Different from current mechanical crushing, heat treatment and chemical operation processes, novel and environment-friendly recycling approaches by using high voltage pulse discharge in water, called high voltage fragmentation (HVF), was discussed under different discharge conditions.

View Article and Find Full Text PDF

Hongkong kumquat (Fortunella hindsii) is a wild citrus species characterized by dwarf plant height and early flowering. Here, we identified the monoembryonic F. hindsii (designated as 'Mini-Citrus') for the first time and constructed its selfing lines.

View Article and Find Full Text PDF

Chloropicrin fumigation had strong inhibitory effect on soil N cycling. Knowledge gap existed about the performance of reactive N in soil applied with different amendments used to improve the fumigation function or soil quality. In this study, we employed four amendments, i.

View Article and Find Full Text PDF

Objective: To investigate the ability of autologous peripheral blood endothelial progenitor cells (EPCs) in promoting neovascularization of tissue engineered bone and osteogenesis of bone marrow mesenchymal stem cells (BMSCs).

Methods: The peripheral blood EPCs and BMSCs from No. 1-9 New Zealand rabbits were isolated, cultured, and identified.

View Article and Find Full Text PDF

Soil fumigation is an important treatment in the production chain of fruit and vegetable crops, but fumigant emissions contribute to air pollution. Biochar as a soil amendment has shown the potential to reduce organic pollutants, including pesticides, in soils through adsorption and other physicochemical reactions. A laboratory column study was performed to determine the effects of soil applications of biochar for reducing emissions of the fumigant 1,3-dichloropropene (1,3-D).

View Article and Find Full Text PDF

Objective: To study the assessment and management for abdominal aortic aneurysm (AAA)'s special distal landing zones in endovascular repair (EVAR).

Methods: The clinic data of 66 AAA patients with complicated distal landing zones From January 2007 to December 2010 was retrospectively analyzed. There were 45 male and 21 female patients, aged from 53 to 87 years with a mean of 62 years.

View Article and Find Full Text PDF