Publications by authors named "Chengke Su"
Aging (Albany NY)
May 2024
Article Synopsis
- Stress contributes to the development of Alzheimer's disease (AD) by causing DNA damage, which leads to cognitive impairment and brain pathology.
- In mice exposed to chronic stress, stress hormones increase DNA damage that activates proteins linked to cancer and tau hyperphosphorylation, resulting in synaptic damage.
- Targeting the DNA damage response and related pathways with specific inhibitors or vitamin C can lessen AD-like symptoms and provide new treatment options.
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