Publications by authors named "Chengjie Yao"

Article Synopsis
  • Leukemia and lymphoma are prevalent blood cancers, affecting both adults and children, with global incidence and mortality rates around 6%.
  • While CAR T cell therapy is costly, natural products from various sources (animals, plants, microorganisms) offer cost-effective alternatives for cancer treatment.
  • Recent research focuses on natural compounds with potential anti-lymphoma and anti-leukemia effects, highlighting the need for new treatments due to drug resistance in current therapies.
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Article Synopsis
  • Gonadotropin-releasing hormone (GnRH) is essential for reproductive regulation in vertebrates, but its function in invertebrates like the crab Eriocheir sinensis has been under-studied and controversial.
  • Researchers identified two GnRH-like peptides in the crab's brain that are linked to oocyte maturation and found that these peptides significantly activate the signaling pathways related to germinal vesicle breakdown (GVBD).
  • The study provides the first evidence of GnRH-like peptides in crabs, highlighting their role in oocyte maturation and confirming that they operate through cAMP and calcium signaling pathways, similar to GnRH functions in vertebrates.
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Vitellogenesis in crustaceans is controlled by several steroid hormones. In humans, the expression of SF-1, a gene that regulates gonadal development and the synthesis of steroid hormones, is affected by DDX20. However, how the homologous gene FTZ-F1 is regulated by DDX20 and its association with vitellogenesis remains unknown in the mud crab Scylla paramamosain.

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Although many studies have shown that lncRNA, a non-coding RNA with a length of more than 200 bases, is involved in various biological functions, including the immune process, stress process, and cell development process. However, the function of lncRNA in abalone, especially in immunity, has been rarely studied. H.

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Myostatin (MSTN) is a negative regulator of muscle growth, which restrains the proliferation and differentiation of myoblasts. To understand the role of two genes of , the full-length cDNAs of 1131 bp and 1,080 bp were obtained from the ' genomic database, which encodes 376 and 359 amino acids, respectively. The results of qRT-PCR showed that was expressed in the eye, kidney, spleen, skeletal muscle, gill, and brain, and the expression level in the skeletal muscle was extremely significantly higher than in other examined tissues.

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Sox transcription factors play essential roles in a variety of critical physiological processes. Still, members of the sox gene family have not yet been genome-wide identified in shrimps. In this study, a total of five members of the sox gene family were identified from the genome of Pacific white shrimp Litopenaeus vannamei and classified into three subgroups based on the conserved HMG-box domain.

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Validamycin, known to interfere with fungal energy metabolism by inhibiting trehalase, has been extensively used to control plant diseases caused by Rhizoctonia spp. However, the effect of validamycin on controlling Fusarium graminearum has not been previously reported. In this study, when applied to F.

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