Background: Conservative treatments have been reported to diminish or resolve clinical symptoms of lumbar intervertebral disc herniation (LIDH) within a few weeks.
Case Summary: Computed tomography and magnetic resonance imaging (MRI) of the lumbar region of a 25-year-old male diagnosed with LIDH showed prolapse of the L5/S2 disc. The disc extended 1.
Zinc is highly enriched in the central nervous system. Numerous evidences suggest that high concentration of zinc acts as a critical mediator of neuronal death in the ischemic brain, however, the possible mechanisms of neurotoxicity of zinc during cerebral ischemia/reperfusion (I/R) remain elusive. Endoplasmic reticulum (ER) is a storage location of intracellular zinc.
View Article and Find Full Text PDFCurrently, miRNA analysis is significant for understanding miRNA regulation networks and clinical diagnostics and therapy. Analytical strategies feasible for multiplex miRNA-sensitive analysis are still in high demand. Herein, we propose a novel strategy for miRNA analysis by coupling cascade amplification with digitally encoded silica microparticles.
View Article and Find Full Text PDFTo solve the problem of unknown state noises and uncertain measurement noises inherent in underwater cooperative navigation, a new Variational Bayesian (VB)-based Adaptive Extended Kalman Filter (VBAEKF) for master⁻slave Autonomous Underwater Vehicles (AUV) is proposed in this paper. The Inverse Wishart (IW) distribution is used to model the predicted error covariance and measurement noise covariance matrix. The state, together with the predicted error covariance and measurement noise covariance matrix, can be adaptively estimated based on VB approximation.
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