Publications by authors named "Chenghao Liang"

Hepatitis C virus (HCV) is responsible for a variety of human life-threatening diseases, which include liver cirrhosis, chronic hepatitis, fibrosis and hepatocellular carcinoma (HCC) . Computational study of protein-protein interactions between human and HCV could boost the findings of antiviral drugs in HCV therapy and might optimize the treatment procedures for HCV infections. In this analysis, we constructed a prediction model for protein-protein interactions between HCV and human by incorporating the features generated by pseudo amino acid compositions, which were then carried out at two levels: categories and features.

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We synthesized a novel material, namely palladized zero-valent zinc (Pd/ZVZ), and investigated its efficiency for the degradation of polybrominated diphenyl ethers (PBDEs). The plated Pd significantly enhances the degradation rate of PBDEs by ZVZ at the optimum loading of 1% by weight. In the Pd/ZVZ system, very few lower BDEs were accumulated during the degradation of 2,2',4,4'- tetrabromodiphenyl ether (BDE-47) and the final product is diphenyl ether, whereas the ZVZ system only debrominates BDE-47 to di-BDE and further debromination becomes very difficult.

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Amorphous hydrated manganese dioxide (MnO2) was prepared as an electrode material for supercapacitors by liquid co-precipitation in the presence of polyvinylpyrrolidone (PVP), polyethylene glycol (PEG) and sodium dodecylbenzenesulfonate (SDBS) respectively. The obtained samples were characterized by x-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), high-resolution transmission electron microscopy (HRTEM), and electrochemical methods. Physical characterizations confirmed that the addition of surfactants played an important role in the preparation of MnO2.

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The electrochemical behaviour of Ti-Ni shape memory alloy and Co-Cr alloys were investigated in dynamic Tyrode's simulated body fluid on a Model CP6 Potentiostat/Galvanostat. The results indicated that, for all alloys, the anodic dissolution and the pitting sensitivity increased with the flow rate of the Tyrode's solution increasing while the open-circuit potentials and pitting corrosion potentials decreased with the Tyrode's solution increasing. Pitting corrosion of Ti-Ni alloy was easier than Co-Cr alloys.

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In this work, the electrochemical characteristic of TiNi shape memory alloy (SMA) in Hank's solution was studied. The results indicated that low potential active dissolution of TiNi SMA occurred at a potential range of 150-250 mV during anodic polarizing. Its corrosion resistance was not affected by temperature, but was deeply affected by pH and Cl- ion concentration.

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Biomedical TiNi shape memory alloy and Co-based alloys were ion implanted, and corrosion resistance and hemocompatibility of these had been investigated with electrochemical method, dynamic clotting time, and hemolysis rate tests. The results indicated that the electrochemical stability and anodic polarization behavior of the materials were improved significantly after ion implantation. When TiNi, Co-based alloys were implanted Mo + C and Ti + C, respectively, the corrosion potentials were enhanced more than 200 mV, passive current densities decreased, and passive ranges were broadened.

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Electrochemical constant current linear polarization and atomic absorption spectroscopy were used to measure the corrosion rate of coronary stents made of 316L and 317L stainless steel in 30 degrees C Tyrode's solution. The results indicated that the corrosion rate of 316L and 317L stainless steel was 21 X 10(-3) microm/a, 9.8 X 10(-3) microm/a and 0.

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The electrochemical mechanism of austenitic stainless steel (SUS316L and SUS317L) coronary stents in flowing artificial body fluid has been investigated with electrochemical technologies. The results indicated that the flowing medium coursed the samples' pitting potential Eb shift negatively, increased the pitting corrosion sensitivity, accelerated its anodic dissolution, but had little effects on repassivated potential. The flowing environment had great effects on cathodic process.

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Chemical immersion tests, electrochemical methods and atomic absorption spectrometry were employed to investigate the corrosion behavior of Cu and the Cu-Zn-Al shape memory alloy (SMA) in simulated uterine fluid. The effect of pH on corrosion rate and corrosion potential was also investigated. The results indicated that in the static state in simulated uterine fluid, dealuminumification of the Cu-Zn-Al alloy occurred with Cl- combining with aluminum ions to form hydroxyl aluminum chloride.

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The corrosion rates of TiNi, CoCrNiW and CoCrNiMo were measured in Tyrode's solution with potentiodynamic linear polarization, fore-point weak polarization, Cao Chunan weak polarization, transient linear polarization and atomic absorption spectroscopy. Results indicated that corrosion rates of these three alloys were very low due to their excellent corrosion resistance and the corrosion resistance of CoCrNiMo was the best. Corrosion rates of TiNi, CoCrNiW and CoCrNiMo were 0.

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