Development of a Microfluidic Formatted Ultrasound-Controlled Monodisperse Lipid Vesicles' Hydrogel Dressing Combined with Ultrasound for Transdermal Drug Delivery System.

Transdermal drug delivery system (TDDS) has attracted much attention in the pharmaceutical technology area. However, the current methods are difficult to ensure penetration efficiency, controllability, and safety in the dermis, so its widespread clinical use has been limited. This work proposes an ultrasound-controlled monodisperse lipid vesicles (U-CMLVs) hydrogel dressing, which combines with ultrasound to form TDDS.

New Insight into Assembled FeO@PEI@Ag Structure as Acceptable Agent with Enzymatic and Photothermal Properties.

Metal-based enzyme mimics are considered to be acceptable agents in terms of their biomedical and biological properties; among them, iron oxides (FeO) are treated as basement in fabricating heterogeneous composites through variable valency integrations. In this work, we have established a facile approach for constructing FeO@Ag composite through assembling FeO and Ag together via polyethyleneimine ethylenediamine (PEI) linkages. The obtained FeO@PEI@Ag structure conveys several hundred nanometers (~150 nm).

A rational synthesis of ultrasmall palladium-based alloys with superhydrophilicity as biocompatible agents and recyclable catalysts.

As essential controlling parameters, the local surface area (size distribution) and polarity property of the surface molecules can determine the catalytic activity and biocompatibility directly. Here, ultrasmall palladium-based alloys (FePd, FePdCo, and FePdCu NCs) were developed to serve as artificial degradation catalysts with superhydrophilicity (SPh), biocompatibility, and reusability, which were referred to as "biocatalysts". As synthesized in aqueous solvent with negative surface potential while dispersing in water medium, because of the surface biological molecules effect.

Assembling Alkaline-Responsive Chitosan@Giant Liposomes through an Ultrasound-Integrated Microfluidic Approach.

This paper presents the fabrication of an alkaline-responsive drug carrier, chitosan@giant liposome (CS-GL), by using an ultrasound-integrated microfluidic approach. On the microfluidic chip, water/oil/water droplets are first prepared and then move through an area of ultrasonic radiation to improve the regional saturation of organic solvent and accelerate its removal. At the same time, phospholipid molecules in the oil phase of the droplets are efficiently self-assembled into giant liposomes (GLs).

Recent Advances in Metal-Based Magnetic Composites as High-Efficiency Candidates for Ultrasound-Assisted Effects in Cancer Therapy.

Metal-based magnetic materials have been used in different fields due to their particular physical or chemical properties. The original magnetic properties can be influenced by the composition of constituent metals. As utilized in different application fields, such as imaging monitoring, thermal treatment, and combined integration in cancer therapies, fabricated metal-based magnetic materials can be doped with target metal elements in research.