Publications by authors named "Chengcai Xu"
Article Synopsis
- - The NICHE trial highlighted the effectiveness of neoadjuvant immunotherapy in colorectal cancer patients with mismatch repair (MMR) deficiency, but only 10% of rectal cancer patients have this deficiency, prompting the need for better treatments for MMR-proficient patients.
- - The study proposes a phase II trial called the NECI Study that will combine neoadjuvant arterial embolisation chemotherapy (NAEC) with oxaliplatin, immunotherapy using tislelizumab, and the XELOX chemotherapy regimen to enhance treatment effects for locally advanced rectal cancer.
- - This is the first multicenter, prospective, single-arm trial designed to evaluate the safety and effectiveness of this combination therapy, aiming to develop
Parachute-like pull-through anastomosis for low rectal cancer: a new method for preservation of anal function.
Langenbecks Arch Surg
February 2023
Background: With recent improvements in surgical technique, oncological outcomes of low rectal cancer have improved over time. But the QoL impairment as a result of anal functional disorder cannot be ignored. And the incidence of anastomosis-related complications cannot be ignored.
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