Network-level crash risk analysis using large-scale geometry features.

Road traffic crashes are common occurrences that create substantial losses and hazards to society. A complex interaction of components, including drivers, vehicles, roads, and the environment, can impact the causes of these crashes. Due to its complexity, crash identification, and prediction research over large-scale areas faces several obstacles, including high costs and challenging data collecting.

Rapid Isolation of Stage I Oocytes in Zebrafish Devoid of Granulosa Cells.

The study of oocyte development holds significant implications in developmental biology. The zebrafish (Danio rerio) has been extensively used as a model organism to investigate early developmental processes from oocyte to embryo. In zebrafish, oocytes are surrounded by a single layer of somatic granulosa cells.

Structural integrity of aging steel bridges by 3D laser scanning and convolutional neural networks.

For steel bridges, corrosion has historically led to bridge failures, resulting in fatalities and injuries. To enhance public safety and prevent such incidents, authorities mandate in-situ evaluation and reporting of corroded members. The current inspection and evaluation protocol is characterized by intense labor, traffic delays, and poor capacity predictions.

LncRNA-mRNA coexpression analysis reveals distinct pathogenic mechanisms for subtypes of congenital biliary dilatation.

Background/purpose: Congenital biliary dilatation (CBD) is a bile duct malformation often associated with pancreaticobiliary maljunction. Different subtypes of CBD have been noted for clinical differences, but their pathogenic mechanisms are unclear.

Methods: To elucidate the genetic basis of CBD, we performed lncRNA and mRNA sequencing and bioinformatic analysis on 18 cystic and 18 fusiform CBD samples.

Corrigendum: Molecular characteristics of choledochal cysts in children: transcriptome sequencing.

[This corrects the article DOI: 10.3389/fgene.2021.

Case Report: Pancreatic and hepatic kaposiform hemangioendothelioma presenting as consumptive coagulopathy and right hepatic atrophy.

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that causes progressive angiogenesis and lymphangiogenesis, which often occurs in the skin or soft tissue, with an acute onset and rapid progression. A 4-year-old girl was admitted to our hospital with a 2-year history of thrombocytopenia, combined with right hepatic atrophy and pancreatic lesion for 3 months. At the age of two, she developed purpura and thrombocytopenia was detected, after treatment with gamma globulin and corticosteroids, the platelet count normalized, but it dropped immediately at lower doses.

Roux-en-Y hepaticojejunostomy or hepaticoduodenostomy for biliary reconstruction after resection of congenital biliary dilatation: a systematic review and meta-analysis.

The ideal surgical management for reconstruction after excision of congenital biliary dilatation remains controversial. This updated meta-analysis compared the clinical outcomes of hepaticoduodenostomy (HD) and hepaticojejunostomy (HJ) after resection of congenital biliary dilatation. PubMed, Web of Science, Embase, Ovid, and the Cochrane Library were searched for studies published from November 1981 through July 2020.

Crash proximity and equivalent property damage calculation techniques: An investigation using a novel horizontal curve dataset.

Despite the numerous breakthroughs in crash analytics, there remains a lack of consensus among safety practitioners as to the optimal method for locating high crash locations. Two critical components in the traffic safety analysis process not agreed upon are 1) how the crash distance to a target location is included in the analysis and 2) how crashes are weighted based on crash-related characteristics. For example, the commonly used buffering technique to determine which crashes are associated with a specific target road segment does not associate crashes that are closer to a target road segment with any additional weight, even though it is likely to be more greatly associated with the characteristics of the target location.

Preliminary Experiences With Robot-Assisted Choledochal Cyst Excision Using the Da Vinci Surgical System in Children Below the Age of One.

The purpose of this study is to introduce our preliminary experiences with using the da Vinci surgical system to treat choledochal cysts in children under 1 year old and discuss the application of this robot-assisted surgery. We retrospectively analyzed all available clinical data of children below the age of 1 who underwent surgery for choledochal cysts using the da Vinci robotic surgical system between January 2015 and December 2020. Data collection mainly included demographic information, imaging data, perioperative details, and postoperative outcomes.

Molecular Characteristics of Choledochal Cysts in Children: Transcriptome Sequencing.

A choledochal cyst (CC) is a common congenital biliary disease in children, yet the underlying molecular bases for the cystic and fusiform clinical subtypes are unknown. RNA sequencing (RNA-seq) has been performed on 22 high-quality CC samples, including 12 cystic CC and 10 fusiform CC samples, to search for molecular features. Weighted gene co-expression network analysis (WGCNA) was performed to identify key modules associated with clinical subtypes.

Investigating the effectiveness of safety countermeasures at highway-rail at-grade crossings using a competing risk model.

Introduction: Highway-rail at-grade crossings (HRGCs) are critical locations where a railway and a roadway intersect with one another. Crashes at those locations often result in fatalities and economic and social damages due to the impacts on both road and rail users. The main purpose of countermeasures at HRGCs is to permit safe and efficient rail and highway operations.