Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways.

Introduction: Osteosarcoma (OS), a prevalent metastatic cancer among young individuals, is associated with a grim prognosis. Long non-coding RNAs (lncRNAs), including C1QTNF1-AS1, are pivotal regulators of cancer cell proliferation and motility. As an oncogene, C1QTNF1-AS1 is implicated in various tumor types, such as colorectal, pancreatic, hepatocellular carcinomas, and OS.

Foraminoplasty at the Base of the Superior Articular Process with Bone Drilling for Far-Downward Discs in Percutaneous Endoscopic Lumbar Discectomy: A Retrospective Study.

Purpose: Percutaneous endoscopic lumbar discectomy (PELD) is usually used to treat lumbar disc herniation (LDH). This study aims to describe PELD by foraminoplasty in the treatment of far-downward migrated LDH and to demonstrate the clinical efficacy by a retrospective evaluation.

Patients And Methods: Between January 2017 and July 2018, 41 patients with far-downward migrated LDH were treated with PELD by foraminoplasty at the base of the superior articular process (SAP).