[Establishment of animal model of myoclonus originating from axis of cortex-thalamus].

Objective: To develop a series of experimental animal models of myoclonus with different origins consistent with myoclonus seizure in clinic setting.

Methods: GABA(A) antagonist SR95531 was microinjected into the primary motor cortex (PMC), corpus striatum, nucleus reticular of the thalamus (NRT) to induce myoclonus (EMG burst of myoclonus View Article and Find Full Text PDF