Publications by authors named "Cheng-dong Piao"

Background: Currently, open reduction internal fixation is the conventional surgical method for treatment of double ulna and radius fracture. However, open reduction is associated with a high risk of complications. This case of forearm double fracture involved a patient treated using an Acumed intramedullary nail.

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Article Synopsis
  • Lungs are the main sites where osteosarcomas spread, contributing to high mortality rates, and recent studies highlight the significance of long non-coding RNAs (lncRNAs) in osteosarcoma cell growth.
  • Comparison of lncRNA levels in osteosarcoma tumors with and without lung metastasis revealed that MALAT1 is significantly upregulated in metastasized cases, suggesting its role in promoting lung spread.
  • The research indicates that downregulating MALAT1 reduces the invasive potential of osteosarcoma cells and affects the miRNA miR-202, hinting that the MALAT1-miR-202 interaction could be a promising target for new therapies against lung metastasis in osteosarcoma.
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Rationale: Obturator dislocation of the femoral head combined with ipsilateral femoral neck and pubic fracture is a rare injury. We used cannulated screws combined with a femoral neck medial plate for the first time to treat this type of injury and achieved good follow-up results.

Patient Concerns: The patient was hospitalized due to an accident resulting in swelling and deformity accompanied by limited mobility of the right hip and left knee.

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In the repair of peripheral nerve injury using autologous or synthetic nerve grafting, the magnitude of tensile forces at the anastomosis affects its response to physiological stress and the ultimate success of the treatment. One-dimensional stretching is commonly used to measure changes in tensile stress and strain; however, the accuracy of this simple method is limited. Therefore, in the present study, we established three-dimensional finite element models of sciatic nerve defects repaired by autologous nerve grafts.

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Bone marrow mesenchymal stromal cells (BMSCs) are the common precursors for both osteoblasts and adipocytes. With aging, BMSC osteoblast differentiation decreases whereas BMSC differentiation into adipocytes increases, resulting in increased adipogenesis and bone loss. In the present study, we investigated the effect of asiatic acid (AA) on adipocytic differentiation of BMSCs.

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