Publications by authors named "Cheng-Zhi Li"

Mineral elements typically act as transported substrates for metal tolerance proteins (MTPs). The chelation of MTPs with heavy metal ions is a suggestive detoxification pathway in plants; therefore, the trade-off between transporting mineral elements and chelating excess toxic metal ions is inevitable. Gallium (Ga) is an emerging pollutant associated with high-tech industries.

View Article and Find Full Text PDF
Article Synopsis
  • * The research used network pharmacology and various laboratory techniques to identify PA's core action on NAFLD, revealing PPAR-α as a key target of intervention.
  • * Findings showed that low-dose PA treatment significantly improved liver fat deposition and reduced damage in NAFLD mice by enhancing protective proteins and decreasing harmful ones.
View Article and Find Full Text PDF
Article Synopsis
  • Plants are increasingly challenged by environmental pollutants and high levels of carbon dioxide (CO2), prompting researchers to investigate the combined effect of elevated CO2 and cyanide on rice seedlings grown hydroponically under nitrogen deficiency.
  • The study found that higher CO2 levels improved growth in rice seedlings treated with cyanide, significantly influencing gene expression and amino acid metabolism.
  • Overall, the findings suggest that using elevated CO2 can enhance plant growth while managing nitrogen pollution, presenting a new strategy for rice cultivation in nitrogen-deficient conditions.
View Article and Find Full Text PDF

Potential toxic element (PTE) pollution has emerged as a significant environmental and social concern in global agriculture. Chromium (Cr) occurs in different oxidation states naturally, among them Cr(VI), which is highly toxic. This study carried out biochemical and molecular tests to elucidate the accumulation of total soluble phenolics (TSPs) in rice plants exposed to Cr(VI) at 2.

View Article and Find Full Text PDF
Article Synopsis
  • Vascular aging is linked to problems in blood vessel cells, including DNA damage and inflammation, which worsen as we get older.
  • Researchers discovered that a protein called STING is involved in making these aging problems worse by causing inflammation and more DNA damage in the cells.
  • They found that a drug called Cilostazol can help block the harmful effects of STING, making it a potential treatment for diseases related to aging blood vessels.
View Article and Find Full Text PDF

In recent decades, there has been increasing interest in elucidating the role of sulfur-containing compounds in plant metabolism, particularly emphasizing their function as signaling molecules. Among these, thiocyanate (SCN), a compound imbued with sulfur and nitrogen, has emerged as a significant environmental contaminant frequently detected in irrigation water. This compound is known for its potential to adversely impact plant growth and agricultural yield.

View Article and Find Full Text PDF

The development of artificial receptors that combine ultrahigh-affinity binding and controllable release for active guests holds significant importance in biomedical applications. On one hand, a complex with an exceedingly high binding affinity can resist unwanted dissociation induced by dilution effect and complex interferents within physiological environments. On the other hand, stimulus-responsive release of the guest is essential for precisely activating its function.

View Article and Find Full Text PDF

Gallium (Ga) is an emerging chemical pollutant chiefly associated with high-tech industries. Boron (B) alleviates the negative effects of toxic elements on plant growth. Thereby, the effects of B fertilization on Ga toxicity in rice seedlings was studied to clarify the role of iron plaque in the distribution of Ga, Fe, and B in Ga-treated rice seedlings in the presence or absence of B.

View Article and Find Full Text PDF
Article Synopsis
  • - The study explores how boron (B) deficiency impacts the role of H-ATPase in rice seedlings' absorption and processing of cyanide (CN), revealing that B-deficient plants absorb and assimilate CN more effectively than those with adequate B.
  • - Gene expression analysis shows that certain genes related to CN metabolism, specifically β-CAS and ST, are regulated differently in B-deficient plants, indicating a tissue-specific response to nutrient conditions.
  • - Overall, B deficiency alters nitrogen cycling in CN-exposed rice seedlings by enhancing H-ATPase activity, leading to increased CN uptake and assimilation while affecting the natural nitrogen pool produced in the process.
View Article and Find Full Text PDF

The induction of disruption in the electronic transport chain by thiocyanate (SCN) leads to an excessive generation of reactive oxygen species (ROS) within rice (Oryza sativa). Hydrogen sulfide (HS) assumes a crucial role as a gaseous signaling molecule, holding significant potential in alleviating SCN-related stress. Nevertheless, there remains a dearth of understanding regarding the intricate interplay between HS and ROS in Oryza sativa amidst SCN pollution.

View Article and Find Full Text PDF

Plant kingdoms are facing increasingly harsh environmental challenges marked by the coexposure of salinity and pollution in the pedosphere and elevated CO and temperature in the atmosphere due to the rapid acceleration of industrialization and global climate change. In this study, we deployed a hydroponics-based experiment to explore the individual and mutual effects of different temperatures (low temperature, T1: 23°C; high temperature, T2: 27°C) and CO concentrations (ambient CO: 360 ppm; medium CO: 450 ppm; high CO: 700 ppm) on the uptake and translocation of sodium chloride (NaCl, 0.0, 0.

View Article and Find Full Text PDF

Cyanide (CN) pollution in agricultural systems impairs amino acid metabolism in rice plants, hence decreasing their quality and yield. Meanwhile, little is known about the effects of CN assimilation on the innate pool of proline (Pro) and its synthesis-related amino acids (Pro-AAs) in rice plants. In this study, a hydroponic experiment was carried out to investigate the effect of exogenous KCN on indigenous levels of Pro-AAs, i.

View Article and Find Full Text PDF

The biosynthesis of amino acids (AAs) in plants is affected by different nitrogen (N) sources. The effects of exogenous cyanide (KCN) on the concentrations and profiles of AAs in rice seedlings were carried out in the presence of nitrate (+NO)/ammonium (+NH) or N deficiency (-N). Targeted metabolomics analysis indicated that the highest accumulation of AAs in CN-treated rice seedlings was detected in the "CN+NH" treatments than in other treatments, wherein the doses of exogenous KCN did not significantly affect the total amount of AAs in rice seedlings at the same N fertilized condition.

View Article and Find Full Text PDF

Cadmium (Cd) pollution has become a major threat to crop production and quality globally. The heavy metal P-ATPases (HMAs) play a crucial role in metal transport in plants. In the present study, we investigated the interaction in metal transport by HMAs between Cd and mineral elements in rice plants.

View Article and Find Full Text PDF

Thiocyanate (SCN) is a sulfur-containing pollutant, which is frequently detected in irrigation water and has negative effects on plant growth and crop yields. Uptake and assimilation of exogenous SCN in rice plants was evident, in which two metabolic pathways, carbonyl sulfide (COS) and cyanate (CNO), are activated. Hydrogen sulfide (HS) is an important concomitant derived from detoxification of exogenous SCN in rice plants, which may cause coupling action on the endogenous source of HS from sulfur metabolism.

View Article and Find Full Text PDF

In spite of available information demonstrating the assimilation of cyanide (CN) by β-cyanoalanine synthase (β-CAS) in plants, involvement of sulfurtransferase (ST) in CN assimilation in rice plants is still undefined. In this study, a microcosmic hydroponic system was used to investigate the involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in the CN assimilation in rice seedlings under the exposure of potassium cyanide (KCN) in presence or absence of 1-amino-cyclopropane-1-carboxylic acid (ACC). Our results indicated that the measurable thiocyanate (SCN) was detected in both rice roots and shoots under KCN exposure, and the abundances of ST-related transcripts were up-regulated significantly (p < 0.

View Article and Find Full Text PDF

Thiocyanate (SCN) present in irrigation water can have negative effects on plant growth and crop yields. Addition of plant growth regulators (PGRs) can alleviate toxic stress to plants. In the current study, we established a grey situation decision-making model (GSDM) to integrate the data of RT-qPCR analysis for screening the optimal addition of PGRs to minimise pollution stress.

View Article and Find Full Text PDF

Exogenous cyanide (CN) effects on nitrogen (N) uptake, transport, and assimilation in rice seedlings were investigated at the biochemical and molecular levels. Seedlings were treated with either a 2-d or 4-d supply of potassium cyanide (KCN) in the nutrient solution containing nitrate (NO) or ammonium (NH). Although a KCN-induced increase was recorded in the activity of β-cyanoalanine synthase (β-CAS) in rice tissues of both NH-fed and NO-fed seedlings, the former showed a significantly greater assimilation rate for CN than the latter.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to investigate the effectiveness of low-intensity pulsed ultrasound (LIPUS) in repairing ovarian damage caused by cyclophosphamide (CTX) in female rats.
  • After inducing ovarian failure in 43 rats, they were divided into treatment and control groups, with the treatment group receiving LIPUS while the others did not.
  • Results showed that LIPUS improved the rats' estrous cycles, increased the number of ovarian follicles, and raised serum estradiol levels, indicating its potential to aid recovery from ovarian injury caused by CTX.
View Article and Find Full Text PDF

Objective: To establish a SD rat model of vulvar lichen simplex chronicus (LSC) and investigate the expression of protease activated receptor 2 (PAR2) in the genital skin.

Methods: Seventy female SD rats were randomly divided into group A (blank control group, n=10), group B (with application of acetone solution 3 times per week for 10 weeks, n=10), group C (with chronic mechanical irritation 3 times per week for 10 weeks, n=10), and group D (with topical treatment with 0.5= 7,12-Dimethylbenzanthracene [DMBA] in acetone solution and chronic mechanical irritation 3 times per week for 10 weeks, n=40).

View Article and Find Full Text PDF

Objective: To analyze postmortem chemical changes in Landrace costal cartilages and ribs using attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy, and to provide a novel technique for estimation of postmortem interval (PMI).

Methods: The swines were sacrificed by hemorrhage and their costal cartilages and ribs were kept in 20 degrees C. The chemical analysis of the costal cartilages and ribs were performed using ATR-FTIR every 72 h.

View Article and Find Full Text PDF

Aim: To evaluate the outcomes of patients with medium-sized hepatocellular carcinoma (HCC) who underwent percutaneous microwave ablation (MWA).

Methods: We retrospectively reviewed all patients with a single medium-sized HCC who underwent percutaneous MWA from January 2010 to January 2013. Technical success, technical effectiveness and complications were subsequently observed.

View Article and Find Full Text PDF

Objective: To investigate the short and long-term efficacy and complications, as well as the influential factors of focused ultrasound for the treatment of vulva dystrophy.

Methods: Seventy-six eligible patients with vulva dystrophy were randomized and treated with focused ultrasound between 1999 and 2002. Among them, 45 patients were with squamous hyperplasia (SH) and 31 patients were with lichen sclerosus (LS).

View Article and Find Full Text PDF