Publications by authors named "Cheng-Zhi Lei"
Objective: To study the expression of LINC00673 in cervical cancer and cervical intraepithelial neoplasia (CIN) and to explore the role of LINC00673 in the development of cervical cancer.
Methods: The expression of LINC00673 in serum from cervical cancer patients, CIN patients, and healthy participants was detected by RT-qPCR. The function of LINC00673 in cervical cancer cells was analyzed using and experiments.
Article Synopsis
- * Increasing MTF2 levels in HCC cells boosts their growth, migration, and invasion, while reducing its levels has the opposite effect, indicating its role in tumor behavior.
- * MTF2 likely drives these processes by promoting Snail transcription, suggesting that targeting MTF2 could be a new treatment strategy for HCC patients.
Study Objective: To evaluate the detection rate and accuracy of sentinel lymph node (SLN) mapping using cervical and fundal injections of carbon nanoparticles (CNPs) in laparoscopic surgery of endometrioid endometrial cancer (EC) and to identify uterine lymphatic drainage pathways validated by mapping.
Design: A prospective consecutive study (Canadian Task Force classification II-2).
Setting: An academic research center.
Objective: To investigate the relationship between lymph vascular space invasion (LVSI) and various clinicopathologic factors in early-stage cervical squamous carcinoma; to explore the expression of P53, COX2 and CD44V6 in early stage squamous carcinoma of cervix and its relationship with prognosis.
Methods: A case-controlled study was conducted to compare LVSI positive group (n = 44) in early stage squamous carcinoma of cervix with LVSI negative group (n = 44). Expression of P53, COX2 and CD44V6 were evaluated by immunohistochemical method to analyze the relationship between LVSI, P53, COX2 and CD44V6 and various clinicopathologic factors and to investigate their prognostic influences.
[Impact of uterine fibroid embolization with danazol alginate microsphere on ovarian function and subsequent pregnancy].
Zhonghua Fu Chan Ke Za Zhi
October 2007
Objective: To investigate the impact of danazol alginate microspheres used for uterine arterial embolization (UAE) on ovarian function and subsequent pregnancy using rabbit as a model.
Methods: A total of 32 female rabbits were divided into 3 groups: a control group, danazol alginate microspheres (DKMG) group and alginate microspheres (KMG) group. Basal serum estradiol (E(2)), follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T) levels before UAE and 1 - 3 months after UAE were compared for all rabbits.
[Clinical characters and prognosis of postpartum choriocarcinoma].
Zhonghua Fu Chan Ke Za Zhi
November 2006
Objective: To analyze the clinical characters and prognosis of postpartum choriocarcinoma.
Methods: Retrospective analysis of 103 patients diagnosed with postpartum choriocarcinoma in Peking Union Medical College Hospital between 1985 and 2005 was performed.
Results: In a total of 103 cases of postpartum choriocarcinoma treated with multiagent cytotoxic chemotherapy and combined modality therapy, 92 patients (89.