Publications by authors named "Cheng-Yu Chao"
Unlabelled: AMP-activated protein kinase (AMPK) is a metabolic master switch maintaining the energy homeostasis in cells and thought to modulate cellular response to stresses. Adenine as well as a pharmacological AMPK activator, 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), induced the phosphorylation of AMPK and acetyl-CoA carboxylase in NIH/3T3 cells. Administration of adenine or AICAR increased the expression and translocation of glucose transporter 4, enhanced the cellular glucose uptake, and elevated the intracellular ATP level.
View Article and Find Full Text PDFThis work examined the feasibility of ozone (O(3)) absorption by H(2)O(2) solution in a rotating packed bed (RPB). The O(3) removal efficiency was determined at various operating variables including RPB speed, gas flow rate, and liquid flow rate in three RPBs. For each RPB, the results demonstrated that the RPB speed positively affected the O(3) removal efficiency.
View Article and Find Full Text PDFArticle Synopsis
- * The study used gene expression microarrays to analyze how 5-aza-2'-deoxycytidine affected gene expression and cell behavior in liver cancer cells, particularly focusing on gene upregulation and apoptosis.
- * Results indicated that while many genes crucial for tumor growth and regulation were activated, a significant number lacked the typical promoter features associated with methylation, suggesting complex mechanisms of gene regulation at play beyond just methylation inhibition.