Publications by authors named "Cheng-Xian Pi"

Background: Chronic kidney disease (CKD) is very common now and associates with high overall and cardiovascular mortality. Numerous studies have reported that Heart rate variability (HRV) could also be used to detect cardiovascular autonomic dysfunction (CAD). We investigated the association of electrochemical skin conductance (ESC) of EZSCAN results with HRV in non-dialysis CKD patients.

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Background: Diabetic microvascular complications, including diabetic kidney disease (DKD), retinopathy (DR), and neuropathy (DN), were major causes of morbidity and mortality in diabetic patients worldwide. It has been suggested that urinary albumin-to-creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) were not the only indicators of renal function impairment in DKD and that they were also associated with diabetic peripheral neuropathy (DPN) which might affect nerve conduction velocity (NCV). As 30-40% of DPN patients had no subjective symptoms, while current perception threshold (CPT) could detect sensory nerve damage at an early stage.

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Article Synopsis
  • Chronic kidney disease (CKD) is linked to high mortality rates, particularly from cardiovascular issues, and elevated heart rate is identified as a risk factor.
  • A study involving 54 non-dialysis stage 5 CKD patients found that serum endocan levels and hypertension history significantly predict night/day heart rate variability.
  • The results suggest that higher serum endocan is associated with changes in heart rate patterns, indicating a need for further research into treatments that lower serum endocan levels in these patients.
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