Publications by authors named "Cheng-Wen Tan"

Objectives: The aims of this study were to investigate whether serum levels of neurofilaments heavy chain (NfH) and light chain (NfL), neuron-specific enolase (NSE) and S100 calcium binding protein B (S100B): (1) change, (2) alleviate in post-therapy and (3) are associated with sleep quality and cognitive dysfunction, in patients with chronic insomnia disorder (CID).

Methods: Forty CID outpatients constituted free-therapy group (ft-CID), in which twenty-four patients completed follow-up after six-month treatment to form re-visiting group (rv-CID), and twenty healthy good sleepers constituted control group (HC). All subjects completed questionnaires, polysomnography, Chinese-Beijing Version of Montreal Cognitive Assessment (MoCA-C) and Nine Box Maze Test (NBMT) to assess sleep and neuropsychological function.

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Article Synopsis
  • The study looked at how brain damage affects mental health in 388 people over the last 5 years.
  • Most of the people with mental issues from brain injury had some trouble with thinking, often mild.
  • Certain factors, like the type of brain injury and how serious it was, played a big role in how these mental issues showed up.
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