Publications by authors named "Cheng-Tai Choug"
J Hazard Mater
September 2017
Article Synopsis
- Carbon black nanoparticles (CBNs) contribute to atherosclerosis by forming aggregates that can enter the bloodstream and induce endothelial dysfunction in vascular cells.
- The study found that these CBN aggregates caused cell death, increased oxidative stress, and cellular damage in human vascular cells, with their entry into cells observed via transmission electron microscopy.
- Co-treatment with a ROCK inhibitor reduced the negative effects of CBN aggregates, suggesting that the activation of ROCK is a key factor in the endothelial dysfunction caused by these nanoparticles.
