Publications by authors named "Cheng-Qi Shen"
Article Synopsis
- Desmoplastic small round cell tumor (DSRCT) is a highly aggressive cancer with a low 5-year survival rate (15%-30%), typically treated with chemotherapy, radiation, and surgery, but few effective options are available.
- This study highlights three pediatric DSRCT cases successfully treated with anlotinib, a multitarget receptor tyrosine kinase inhibitor, in combination with chemotherapy, leading to reduced tumor size and improved symptoms.
- While one patient experienced complications and passed away post-surgery, the report suggests that anlotinib could be a viable treatment option for children with DSRCT, with manageable side effects like fatigue and hypertension.
Extranodal NK/T-cell lymphoma, nasal type (ENKTL), which is a rare form of mature T/NK cell lymphoma in children, currently lacks a standardized first-line treatment approach. However, a treatment protocol known as the "sandwich" regimen has been used in children newly diagnosed with ENKTL. This protocol combines the administration of methotrexate, ifosfamide, etoposide, pegaspargase, and dexamethasone (referred to as SMILE) with the addition of radiotherapy (RT).
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