Publications by authors named "Cheng-Mei Sun"
Subarachnoid hemorrhage (SAH) is the most devastating form of stroke. Reducing neuronal apoptosis is an important countermeasure against early brain injury (EBI) after SAH. Recent evidence indicates that OX40-OX40L coupling is critical for cell survival and proliferation.
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- The study looked at how a protein called osteopontin (OPN) affects brain cells after a brain injury caused by bleeding (SAH).
- Researchers used rats to test different treatments and measured changes in specific proteins related to cell survival and recycling.
- They found that giving rats OPN improved brain function and helped protect brain cells by reducing harmful proteins that cause cell death.