[Progress of the application research of acupuncture anesthesia in thyroid surgery].

This article reviews the clinical studies on the application of acupuncture anesthesia in thyroid surgery over the past 5 years. Starting from the principle of acupuncture anesthesia, the authors explore the application of acupuncture anesthesia in thyroid surgery, its advantages and development. The summarized findings showed that acupuncture anesthesia has a better analgesic effect in thyroid surgery, which can reduce the occurrence of stress reactions, adverse reactions and complications, and is conducive to postoperative recovery.

An eight-coordinate ytterbium complex with a hexagonal bipyramid geometry exhibiting field-induced single-ion magnet behaviour.

Two isostructural eight-coordinate complexes Ln(NO3)3(tBu3PO)2 (Ln = Yb, 1-Yb; Tb, 2-Tb) were synthesized and structurally analyzed by single-crystal X-ray crystallography. Both complexes feature a nearly perfect hexagonal bipyramidal LnO8 geometry with ideal D3h symmetry. Magnetic measurements show field-induced slow magnetic relaxation for 1-Yb, thereby presenting the first report of YbIII-based SIMs with a hexagonal bipyramidal coordinate geometry.

Serum autoantibodies against a panel of 15 tumor-associated antigens in the detection of ovarian cancer.

In this study, enzyme-linked immunosorbent assay has been used to examine the frequencies of serum autoantibodies against two candidate tumor-associated antigens intensively selected from the Human Protein Atlas database, in combination with 13 tumor-associated antigens available from our lab in sera from 44 OC patients and 50 normal healthy controls. Conventional evaluation (mean + 3SD as the cutoff value to determine a positive reactivity), receiver operating characteristic curve analyses, and classification tree analysis were further used to evaluate the diagnostic performance of autoantibodies against these tumor-associated antigens (anti-tumor-associated antigens) in ovarian cancer. For single anti-tumor-associated antigen, when the cutoff values were set as mean + 3SD of normal healthy controls, NPM1, MDM2, PLAT, p53, and c-Myc could achieve sensitivity higher than 20% at 98% specificity.

The effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppression.

Cervical cancer is a cause of cancer death, making it as the one of the most common cause for death among women globally. Though many studies before have explored a lot for cervical cancer prevention and treatment, there are still a lot far from to know based on the molecular mechanisms. Janus kinase 2 (JAK2) has been reported to play an essential role in the progression of apoptosis, autophagy and proliferation for cells.

Autoantibody response to Sui1 and its tissue-specific expression in hepatocellular carcinoma.

To investigate the immunogenicity of Homo sapiens putative translation initiation factor (Sui1) in hepatocellular carcinoma (HCC), enzyme-linked immunosorbent assay (ELISA) and Western blot were utilized to assess autoantibody responses to Sui1 in sera from HCC patients and healthy individuals. Indirect immunofluorescence (IIF) assay with cancer cells and immunohistochemistry (IHC) study with tissue array slides were performed to examine Sui1 expression profile in cancer cells and tissues. The data confirmed that the frequency of autoantibody to Sui1 in sera of HCC patients was 15.

[Discussion on acupuncture for cerebral apoplexy from the view of rehabilitation].

Abundant experiences have already been accumulated in treatment of stroke with acupuncture. Development of rehabilitation theory also brings unprecedented opportunity and challenge to acupuncture. Combined with the modern rehabilitation theory and practice, it is very helpful to deepen the understanding on treatment of acupuncture for cerebral apoplexy and enhance the therapeutic effect in clinic by studying the mechanism of acupuncture treatment, opportunity of intervention, selection of acupoints, needling manipulations and quantity of stimulations etc.

Magneto-structural correlations in a family of Fe(II)Re(IV)(CN)2 single-chain magnets: density functional theory and ab initio calculations.

Until now, the expressions of the anisotropic energy barriers Δξ and ΔA, using the uniaxial magnetic anisotropy D, the intrachain coupling strength J, and the high-spin ground state S for single-chain magnets (SCMs) in the intermediate region between the Ising and the Heisenberg limits, were unknown. To explore this relationship, we used density functional theory and ab initio methods to obtain expressions of Δξ and ΔA in terms of D, J, and S of six R4Fe(II)-Re(IV)Cl4(CN)2 (R = diethylformamide (1), dibutylformamide (2), dimethylformamide (3), dimethylbutyramide (4), dimethylpropionamide (5), and diethylacetamide (6)) SCMs in the intermediate region. The ΔA value for compounds 1-3 was very similar to the magnetic anisotropic energy of a single Fe(II), while the value of Δξ was predicted using the exchange interaction of Fe(II) with the neighboring Re(IV), which could be expressed as 2JSReSFe.

Exchange coupling and magnetic anisotropy in a family of bipyrimidyl radical-bridged dilanthanide complexes: density functional theory and ab initio calculations.

The origin of the magnetic anisotropy energy barriers in a series of bpym(-) (bpym = 2,2'-bipyrimidine) radical-bridged dilanthanide complexes [(Cp*2Ln)2(μ-bpym)](+) [Cp* = pentamethylcyclopentadienyl; Ln = Gd(III) (1), Tb(III) (2), Dy(III) (3), Ho(III) (4), Er(III) (5)] has been explored using density functional theory (DFT) and ab initio methods. DFT calculations show that the exchange coupling between the two lanthanide ions for each complex is very weak, but the antiferromagnetic Ln-bpym(-) couplings are strong. Ab initio calculations show that the effective energy barrier of 2 or 3 mainly comes from the contribution of a single Tb(III) or Dy(III) fragment, which is only about one third of a single Ln energy barrier.

Understanding the magnetic anisotropy in a family of N2(3-) radical-bridged lanthanide complexes: density functional theory and ab initio calculations.

Density functional theory (DFT) and ab initio methods were used to investigate the influence of both intramolecular exchange coupling and single-ion anisotropy on the relaxation barriers of a series of N2(3-) radical-bridged lanthanide complexes [{[(Me3Si)2N]2(THF)Ln}2(μ-η(2):η(2)-N2)](-) (Ln = Gd(III) (1), Tb(III) (2), Dy(III) (3), Ho(III) (4), and Er(III) (5)) reported by Long and co-workers. DFT calculations show that the exchange coupling between the lanthanide ions is very weak, but the Ln-N2(3-) coupling is strong for each complex. Moreover, the exchange couplings of Ln-N2(3-) are antiferromagnetic for Ln = Gd(III), Tb(III), Dy(III), and Ho(III) but ferromagnetic for Er(III) for the nearly orthogonal magnetic orbitals on Er(III) and N2(3-).

[Clinical observation on idiopathic sudden hearing loss treated by warming-promoting needling technique].

Objective: To explore the effective therapeutic method in the treatment of idiopathic sudden hearing loss (ISHL).

Methods: One hundred and eighty-eight cases of ISHL were randomized into a warming-promoting needling group (74 cases), a conventional acupuncture group (56 cases) and a medication group (58 cases). In the conventional acupuncture group, the conventional needling technique was applied to Baihui (GV 20), Fengchi (GB 20), Yifeng (TE 17), Tinggong (SI 19), Touqiaoyin (GB 11) and Zhigou (TE 6) on the affected side.

Exploring the sources of the magnetic anisotropy in a family of cyanide-bridged Ni9Mo6 and Ni9W6 systems: a density functional theory study.

A density functional theory (DFT) study of the magnetic coupling interactions and magnetic anisotropy in a family of experimentally synthesized Ni(9)Mo(V) and Ni(9)W(V) systems is presented. Our calculations show that for all of our selected Ni(9)M(6) systems, the intramolecular magnetic coupling interactions are ferromagnetic, and the ground-state spins are 12. All of the D values of Ni(9)W(6) systems come mainly from the contribution of the D(i) of W(6)(CN)(48)Ni extracted from Ni(9)W(6), and the influence of the eight surrounding Ni including the ligands on their magnetic anisotropy is very small.

Theoretical study of magnetostructural correlations in a family of triangular manganese(III) complexes.

A theoretical density functional study of the magnetostructural correlations in a family of triangular [Mn(3)O](7+) systems is presented. Our calculations show that to obtain a good [Mn(3)O](7+) system with strong Mn-Mn ferromagnetic interactions and a large negative D value, we can first decrease tau formed by the two planes of Mn(1)NO(2-) and Mn(2)OO(2-) through changing the orientations of the terminal ligands involving mu-NO exchange pathways (this operation will weaken the Mn-Mn ferromagnetic interactions) to obtain a large negative D value, and then increase tau through distorting Mn-N-O-Mn angles and/or enlarge d (the deviation of the mu(3)-O(2-) ion from the [Mn(III)(3)] plane) to enhance the Mn-Mn ferromagnetic interactions.

On the origin of magnetic anisotropy in cyanide-bridged Co(9)M(6) (M = Mo(V) or W(V)) systems: a DFT study.

Our calculations show that the substitution of metal ions using Co(II) is not the main reason that Co(II)(9)M(6) (M = Mo(V) or W(V)) exhibits single-molecule-magnet behavior, whereas the unsymmetrical distribution of three CH(3)OH ligands surrounding each Co(II) is the main one.

Magnetic anisotropy in a family of experimentally synthesized and theoretically modeled M'6M8(CN24) systems.

A theoretical density functional study of the magnetic coupling interactions and magnetic anisotropy in a family of experimentally synthesized and theoretically modeled M'6M8(CN24) (M'=Cu(II), Ni(II) or Co(II); M=Fe(III) or Cr(III)) systems is presented. The calculations show that the interactions in the selected M'6M8(CN24) are all ferromagnetic and the near cubic symmetry of Cu6Fe8 is the origin of its negative magnetic anisotropy parameter D.

Theoretical study of the exchange coupling substituting Mo(V) with W(V) in four cyano-bridged M'9M6 (M' = Mn(II) or Ni(II); M = Mo(V) or W(V)) systems.

Magnetic properties of four high-spin molecules [M'{M'(MeOH)3}8(mu-CN)30{M(CN)3}6] (M' = Mn(II) and M = Mo(V) for A; M' = Mn(II) and M = W(V) for B; M' = Ni(II) and M = Mov for C; M' = Ni" and M = W(V) for D) have been investigated using hybrid density functional theory (DFT) B3LYP with LANL2DZ basis set. Our calculations suggest that models [M'(mu-CN)6{M(CN)7}6](16-) (M' = Mn(II) and M = Mo(V) for A6; M' = Mn" and M = W(V) for B6; M' = Ni(II) and M = Mo(V) for C6; M' = Ni(II) and M = W(V) for D6) and [M'(MeOH)3(mu-CN)3{M(CN)7}3](7-) (M' = Mn(II) and M = Mo(V) for A3; M' = Mn(II) and M = W(V) for B3; M' = Ni(II) and M = Mo(V) for C3; M' = Ni(II) and M = W(V) for D3) are good candidates to model the complete molecular structures of A, B, C and D. For all complexes and models, the antiferromagnetic or ferromagnetic exchange interactions through equatorial cyanides are all stronger than those through apical cyanides.

Theoretical study of the relationship between the nearest-neighbor exchange coupling interactions and the number of peripheral complexes in the cyano-bridged CrMn6(CN)6 and CrMn2(CN)2 clusters.

A theoretical density functional study of the relationship between the nearest-neighbor constants and the number of peripheral complexes in the cyano-bridged [Cr[CNMn(salen)(H2O)]6]3+ and [(5-Brsalen)2(H2O)2Mn2Cr(CN)6] clusters is presented. Two approaches show that the antiferromagnetic coupling interactions between nearest neighbors decrease with the increase of the number of peripheral complexes, although the second approach provides better results using several exchange-correlation functionals. The first approach consisted of evaluating the exchange coupling constant J(ij) between two paramagnetic metal centers i and j in the hexanuclear molecule by calculating the energy differences between the highest and broken-symmetry spin states of a model molecule in which metal atoms except for i and j are substituted by diamagnetic Zn(II) cations, while the second consisted of calculating the different spin-state energies of hexanuclear complexes and using the Heisenberg Hamiltonian to obtain the exchange coupling constants between different metal centers.