Publications by authors named "Cheng-Hao Simon Chien"
Article Synopsis
- The study investigates the impact of various drugs on the heart's JTpeak (JTpc) interval using ECG technology, as part of the CiPA initiative aimed at improving drug safety assessment.
- Researchers compared the performance of three ECG device companies (AMPS, Mortara, and Philips) against FDA technologies, using a dataset of 5,232 ECGs provided by the FDA.
- The findings indicate that while the JTpc interval can effectively differentiate multi-channel from single-channel blocking drugs, inconsistencies arose in measuring drugs like quinidine and dofetilide due to varying definitions of T-wave peak locations when T-wave shapes are irregular.
Background: Interpretation of a patient's 12-lead ECG frequently involves comparison to a previously recorded ECG. Automated serial ECG comparison can be helpful not only to note significant ECG changes but also to improve the single-ECG interpretation. Corrections from the previous ECG are carried forward by the serial comparison algorithm when measurements do not change significantly.
View Article and Find Full Text PDFAutomated discrimination of proximal right coronary artery occlusion from middle-to-distal right coronary artery occlusion and left circumflex occlusion in ST-elevation myocardial infarction.
J Electrocardiol
November 2012
Background: Classifying the location of an occlusion in the culprit artery during ST-elevation myocardial infarction (STEMI) is important for risk stratification to optimize treatment. We developed a new logistic regression (LR) algorithm for 3-group classification of occlusion location as proximal right coronary artery (RCA), middle-to-distal RCA or left circumflex (LCx) coronary artery with inferior myocardial infarction. We compared the performance of the new LR algorithm with the recently introduced decision tree classifier of Fiol et al (Ann Noninvasive Electrocardiol.
View Article and Find Full Text PDFAutomated discrimination of proximal right coronary artery occlusion from middle-to-distal right coronary artery occlusion and left circumflex occlusion in ST-elevation myocardial infarction.
J Electrocardiol
May 2012
Background: Classifying the location of an occlusion in the culprit artery during ST-elevation myocardial infarction (STEMI) is important for risk stratification to optimize treatment. We developed a new logistic regression (LR) algorithm for 3-group classification of occlusion location as proximal right coronary artery (RCA), middle-to-distal RCA or left circumflex (LCx) coronary artery with inferior myocardial infarction. We compared the performance of the new LR algorithm with the recently introduced decision tree classifier of Fiol et al (Ann Noninvasive Electrocardiol.
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