Publications by authors named "Cheng-Che Chou"
Background: The clinical presentations of abusive head trauma can abruptly worsen, so the occurrence of seizures and changes of EEG can be variable according to patients' conditions. Since the changes of EEG background waves reflect the cortical function of children, we aimed to find out whether the timing of EEG background, epileptiform discharges and seizure patterns were associated with the outcomes of patients with AHT.
Material And Methods: Using seizure type and acute stage electroencephalographic (EEG) characteristics to assess adverse neurological outcomes in children with seizures secondary to abusive head trauma (AHT).
Children have been reported to be less affected and to have milder severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection than adults during the coronavirus disease 2019 (COVID-19) pandemic. However, children, and particularly those with underlying disorders, are still likely to develop critical illnesses. In the case of SARS-CoV-2 infection, most previous studies have focused on adult patients.
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- The study investigates the clinical features of COVID-19 in pediatric patients in Taiwan, focusing on those aged 18 and under.
- The research included 38 pediatric patients from a Northern Taiwan hospital between May and June 2021, finding that asymptomatic cases accounted for nearly half of the sample.
- Key symptoms in symptomatic patients were fever, cough, nasal obstruction, and sore throat, with asymptomatic patients showing higher RT-PCR cycle threshold values, suggesting their infections may be less severe compared to symptomatic cases.
Article Synopsis
- The study aimed to compare the prevalence and risk of thyroid diseases in patients diagnosed with myasthenia gravis (MG) to non-MG controls using Taiwan's health databases.
- The research included 5,813 MG patients and 29,065 matched controls, revealing that MG patients had a significantly higher prevalence of thyroid diseases at diagnosis (18.4% vs. 4.7% in controls) and faced a 2.36-fold increased risk of developing thyroid diseases post-diagnosis.
- The findings indicated that the cumulative probability of developing thyroid diseases over time was substantially greater for MG patients compared to the control group, highlighting a potential link between MG and thyroid conditions.
Background: Myasthenia gravis is the most common disease affecting the neuromuscular junction. The most common etiology among patients with juvenile myasthenia gravis is the production of antibodies against the acetylcholine receptor. However, the clinical outcome in relation to serum levels of anti-acetylcholine receptor antibodies in juvenile myasthenia gravis has rarely been discussed.
View Article and Find Full Text PDFBackground: Nitrous oxide (NO) is a commonly used inhaled anesthetic in outpatient dental procedures. However, the increasing recreational use of NO may result in vitamin B deficiency-related neurologic and psychiatric symptoms. The aim of this study was to demonstrate the clinical features of chronic NO abuse in pediatric patients.
View Article and Find Full Text PDFBackground: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an anti-neuronal antibody-mediated inflammatory brain disease that causes severe psychiatric and neurological deficits in previously healthy patients. The aims of this study were to demonstrate the clinical characteristics of patients diagnosed with anti-NMDA receptor encephalitis and to compare the different treatment strategies among these patients.
Methods: Patients presenting with newly acquired psychiatric and/or neurological deficits were studied retrospectively from 2009 to 2017.
Background: Evidence for the beneficial effect of therapeutic burst-suppression coma in pediatric patients with febrile refractory status epilepticus is limited, and the clinical outcomes of this treatment strategy are largely unknown. Therefore, the aim of this study was to explore the outcomes of therapeutic burst-suppression coma in a series of children with febrile refractory status epilepticus.
Methods: We retrospectively reviewed consecutive pediatric patients with febrile refractory status epilepticus admitted to our pediatric intensive care unit between January 2000 and December 2013.