Publications by authors named "Cheng Sam Qian"
Article Synopsis
- Internal sensory neurons are crucial for monitoring the body's chemical and physical state, helping maintain homeostasis and survival.
- The study focuses on tracheal dendrite (td) neurons in larvae, which are responsive to changes in oxygen and carbon dioxide levels, providing insights into how these neurons sense their environment.
- Key findings reveal that two types of guanylyl cyclases (Gyc88E/Gyc89Db) are essential for detecting low oxygen, while a specific gustatory receptor (Gr28b) is critical for sensing carbon dioxide, especially when larvae are in feeding conditions like burrowing.
Article Synopsis
- - The text discusses how rapid escape behaviors in response to harmful stimuli are crucial for survival, highlighting a lack of understanding regarding the mechanisms linking stimuli to coordinated responses.
- - Researchers identified specific interneurons called Down-and-Back (DnB) neurons in larvae that are activated by harmful heat and are critical for effective escape behaviors, such as body bending and rolling.
- - DnB neurons connect with nociceptive and mechanosensory neurons and interact with pre-motor circuits, coordinating the escape responses by promoting activity in Goro neurons, which are necessary for rolling movements.
Article Synopsis
- The study explores internal sensory neurons, specifically tracheal dendrite (td) neurons, that sense the body's internal state and play a key role in maintaining physiological balance.
- It identifies two distinct classes of td neurons based on their axon projections: one class targets the subesophageal zone (SEZ) in the brain, while the other class connects to the ventral nerve cord (VNC).
- The research highlights the role of a transcription factor called Pdm3 in guiding the axon targeting process of these neurons, indicating potential mechanisms behind how sensory neurons develop and function in monitoring internal conditions.
