An Assessment of Vegetation Changes in the Three-River Headwaters Region, China: Integrating NDVI and Its Spatial Heterogeneity.

Assessing vegetation changes in alpine arid and fragile ecosystems is imperative for informed ecological restoration initiatives and adaptive ecosystem management. Previous studies primarily employed the Normalized Difference Vegetation Index (NDVI) to reveal vegetation dynamics, ignoring the spatial heterogeneity alterations caused by bare soil. In this study, we used a comprehensive analysis of NDVI and its spatial heterogeneity to examine the vegetation changes across the Three-River Headwaters Region (TRHR) over the past two decades.

Activation of CzcS/CzcR during zinc excess regulates copper tolerance and pyochelin biosynthesis of .

Unlabelled: Zinc is an important transition metal that is essential for numerous physiological processes while excessive zinc is cytotoxic. is a ubiquitous opportunistic human pathogen equipped with an exquisite zinc homeostatic system, and the two-component system CzcS/CzcR plays a key role in zinc detoxification. Although an increasing number of studies have shown the versatility of CzcS/CzcR, its physiological functions are still not fully understood.

Competing risk analysis of cardiovascular death in breast cancer: evidence from the SEER database.

Background: Cardiovascular disease (CVD) is the leading cause of death for all non-cancer deaths among breast cancer (BC) patients. The aim of this study was to investigate the risk of cardiovascular mortality (CVM) in patients with BC.

Methods: Patients diagnosed with primary BC between 2010 and 2018 were identified through the Surveillance, Epidemiology and End Results (SEER) database.

A type I-F CRISPRi system unveils the novel role of CzcR in modulating multidrug resistance of .

has abundant signaling systems that exquisitely control its antibiotic resistance in response to different environmental cues. Understanding the regulation of antibiotic resistance will provide important implications for precise antimicrobial interventions. However, efficient genetic tools for functional gene characterizations are sometimes not available, particularly, in clinically isolated strains.

Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem.

Skin is a complex ecosystem colonized by millions of microorganisms, including bacteria, fungi, and viruses. Skin microbiota is believed to exert critical functions in maintaining host skin health. Profiling the structure of skin microbial community is the first step to overview the ecosystem.

Assessing trade-offs among productive, economic, and environmental indicators of forage systems in southern Tibetan crop-livestock integration.

Fostering crop-livestock integration via crop-forage rotation provides opportunities to cope with land degradation, feed deficit, and agropastoral sustainability. Farmers' preferences for forage options are influenced by economic benefit, environmental preference, and productive performance. However, there is little information available on evaluating multiple trade-offs of forage systems for the design of crop-forage rotations.

Tryptophan was metabolized into beneficial metabolites against coronary heart disease or prevented from producing harmful metabolites by the drug screening model based on .

In our previous study of 2,130 Chinese patients with coronary heart disease (CHD), we found that tryptophan (TRP) metabolites contributed to elevated risks of death. Many TRP-derived metabolites require the participation of intestinal bacteria to produce, and they play an important role in the pathogenesis of metabolic diseases such as CHD. So it is necessary to metabolize TRP into beneficial metabolites against CHD or prevent the production of harmful metabolites through external intervention.

CzcR Is Essential for Swimming Motility in Pseudomonas aeruginosa during Zinc Stress.

Two-component system (TCS) plays a vital role in modulating target gene expression in response to the changing environments. Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen that can survive under diverse stress conditions. The great adaptability of P.

OhrR is a central transcriptional regulator of virulence in Dickeya zeae.

Dickeya zeae is the causal agent of rice foot rot disease. The pathogen is known to rely on a range of virulence factors, including phytotoxin zeamines, extracellular enzymes, cell motility, and biofilm, which collectively contribute to the establishment of infections. Phytotoxin zeamines play a critical role in bacterial virulence; signalling pathways and regulatory mechanisms that govern bacterial virulence remain unclear.

Harnessing the CRISPR-Cas Systems to Combat Antimicrobial Resistance.

The emergence of antimicrobial-resistant (AMR) bacteria has become one of the most serious threats to global health, necessitating the development of novel antimicrobial strategies. CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) system, known as a bacterial adaptive immune system, can be repurposed to selectively target and destruct bacterial genomes other than invasive genetic elements. Thus, the CRISPR-Cas system offers an attractive option for the development of the next-generation antimicrobials to combat infectious diseases especially those caused by AMR pathogens.

Effect of Tai Chi and Resistance Training on Cancer-Related Fatigue and Quality of Life in Middle-Aged and Elderly Cancer Patients.

Objective: To study the effect of Tai Chi (TC) and resistance training (RT) with different intensity on the cancer-related fatigue (CRF) and quality of life (QoL) of middle-aged and elderly cancer patients.

Methods: Totally 120 cancer patients were enrolled and randomly assigned to 4 groups by a random number table, including TC group, high-intensity 60% one repetition maximum (1-RM) RT group (HIRT), low-intensity (30% 1-RM) RT group (LIRT) and control group, 30 patients in each group. Participants in the TC group received 24-form simplified Yang-style TC training at a frequency of 40 min per day, 3 days per week for 12 weeks.

Construction of Oxygen-Rich Carbon Foams for Rapid Carbon Dioxide Capture.

As carbon dioxide (CO) adsorbents, porous materials with high specific surface areas and abundant CO-philic groups always exhibit high CO capacities. Based on this consensus, a category of oxygen-rich macroporous carbon foams was fabricated from macroporous resorcinol-formaldehyde resins (PRFs), which were obtained via an oil-in-water concentrated emulsion. By the active effect of potassium hydroxide (KOH) at high temperatures, the resultant carbon foams (ACRFs) possessed abundant micropores with rich oxygen content simultaneously.

Research on Function and Mechanism of Tai Chi on Cardiac Rehabilitation.

With the increasing number of cardiovascular patients, more and more people are living with diseases. Cardiac rehabilitation (CR) is an effective treatment and prevention measure for cardiovascular disease (CVD), which aims to relieve both psychological and physiological stress of CVD, reduce risk of death from CVD, improve cardiovascular function and patients' quality of life. Tai Chi is popular in China and mainly used as a daily leisure activity for the elderly to strengthen their bodies.

The effects of warming and nitrogen addition on ecosystem respiration in a Tibetan alpine meadow: The significance of winter warming.

In recent decades, global warming has become an indisputable fact on the Tibetan Plateau. Alpine ecosystems are very sensitive to global warming, and the impact may depend on the degree of atmospheric nitrogen (N) deposition. The previous studies have paid more attention to year-round warming, but the effect of winter warming has been unstudied.

[Effects of warming and nitrogen addition on community production and biomass allocation in an alpine meadow.].

A long-term experiment, involving exogenous N addition and simulated warming, was conducted in an alpine meadow in Damxung, northern Tibet, to study how warming and N addition influence community production and biomass allocation. The results showed that warming resulted in a warm but dry microsite, that was, air temperature increased by 1.6 ℃ and soil surface temperature increased by 1.

Nanofiber-Based Hydrogels: Controllable Synthesis and Multifunctional Applications.

Nanofiber-based hydrogels (NFHGs) prepared by the combination of traditional hydrogels and novel nanofibers have demonstrated great potential in various application fields, owing to their integrated advantages of superhydrophilicity, high water-holding capacity, good biocompatibility, enhanced mechanical strength, and excellent structural tenability. In this review, a comprehensive overview of the structure design and synthetic strategy of NFHGs derived from electrospinning technique, weaving, freeze-drying, 3D printing, and molecular self-assembling method is provided. The widely researched multifunctional applications, primarily involving tissue engineering, drug delivery, sensing, intelligent actuator, and oil/water separation are also presented.

[Relative factors of recent discovered atrial fibrillation following isolated coronary artery bypass grafting].

Objective: To identify the relative factors of recent discovered atrial fibrillation (AF) following isolated coronary artery bypass grafting (CABG).

Methods: Classified the 649 cases undergoing isolated CABG from January 2005 to December 2006 to two groups according to whether AF appeared after operation. Collected the peri-operative data and operative strategy, then analyzed with single-factor analysis and Logistic regression.

Peratrial closure of atrial septal defects without cardiopulmonary bypass.

The objective of this study was to introduce a new technique for occlusion of an atrial septal defect without cardiopulmonary bypass, using a modified Amplatzer device. Between October 2004 and November 2005, 96 secundum atrial septal defects in 83 patients were occluded by this method. A 3-cm incision in the right 4(th) intercostal space and a minithoracotomy were performed.

[Morphologic and hydrodynamic characteristics of bovine jugular venous conduit with valves].

Objective: To determine the morphologic and hydrodynamic characteristics of bovine jugular venous conduit with valves.

Methods: Fresh bovine jugular veins with a retained native valve procured from a slaughterhouse were used as raw material to fabricate the valved conduits. The hydrodynamic performance of fresh and glutaraldehyde fixed bovine jugular vein conduits with valves was investigated in an experimental flow equipment that provided a constant pressure.