Synopsis of recent research by authors named "Chenfang Dong"
- Chenfang Dong's recent research focuses on understanding the mechanisms driving aggressiveness in basal-like breast cancer (BLBC) and triple-negative breast cancer (TNBC), with an emphasis on specific molecular targets such as AMD1, IMPA2, and PRKCD_pY313 that contribute to cancer progression.
- Key findings reveal that overexpression of genes like AMD1 and IMPA2 correlates with aggressive characteristics in BLBC, indicating that these genes could serve as potential therapeutic targets for intervention.
- Dong's work includes exploring innovative therapies, such as the combination of oncolytic virotherapy with paclitaxel, which shows potential for enhancing breast cancer treatment efficacy, alongside detailed phosphoproteomic studies that identify aberrantly activated kinases in cancer's metabolic reprogramming.
