Predictive value of triglyceride glucose index in acute kidney injury in patients with severe traumatic brain injury.

Background At present, the relationship between the Triglyceride-glucose index (TyG index) and Acute kidney injury (AKI) in traumatic brain injury patients in the Intensive Care Unit (ICU) is still unclear. Currently, the relationship between TyG index and AKI occurred within 7 days in the ICU is a highly researched and trending topic. Objective In this study, we conducted in-depth exploration of the relationship between the development of AKI in traumatic brain injury (TBI) patients in the ICU and changes in TyG index, as well as its relevance.

[Effects of Fusobacterium nucleus derived outer membrane vesicles on claudin-4 expression in oral epithelial cells].

Purpose: To investigate the effect of outer membrane vesicles (OMVs) secreted by Fusobacterium nucleatum (F.n) on Claudin-4 of human oral keratinocytes (HOK) and oral epithelial barrier function.

Methods: Fusobacterium nucleatum was cultured under anaerobic conditions.

Intralesional and peripheral plasma of oral lichenoid reactions exhibit different cytokine profiles: A preliminary study.

Background/purpose: Oral lichenoid reactions (OLRs) are commonly characterized by the infiltration and activation of inflammatory cells at the interface of the oral mucosa. This study aimed to compare the cytokine profiles between intralesional and peripheral plasma from patients with OLRs and elucidate the cytokine profile in the OLR microenvironment.

Materials And Methods: A total of 26 paired intralesional and peripheral plasma samples were collected from patients with OLRs.

[Experimental study on the structure and immune cell phenotypes of the lymphoid tissues in oral lichenoid lesions].

Purpose: To evaluate the existence of tertiary lymphoid structures(TLS) in oral lichenoid lesions and its compositional characteristics of immune cells.

Methods: Tissue samples of normal oral mucosa, oral lichen planus (OLP) and oral lichenoid tissue reaction(OLTR) were collected, thirty cases in each group. Hematoxylin-eosin(H-E) staining was performed to identify the TLS-like structures, and immunohistochemistry (IHC) staining was applied to assess the structure and amount of infiltrating CD3+ T cells, CD19+, CD20+ B cells, CD21+ follicular dendritic cells (FDC), Bcl-6+ germinal centers, CD34+ PNAd+ venules and CD34+ Gp36+ micro lymphatic vessels in TLS of OLL.

Reduction-oxidation series coupling degradation of chlorophenols in Pd-Catalytic Electro-Fenton system.

Organochlorine pesticides are widespread in soils, sediments and even in groundwater, causing great concern to human health because of its toxicity and carcinogenic effects. The remarkable mineralization and lowered toxicity are particularly important during the removal of organochlorine pesticides. In this study, Pd/CeO was prepared and employed as a bifunctional catalyst, to construct the reduction-oxidation series coupling Electro-Fenton (EF) system.

TRIM21 causes abnormal expression of IL-6 in oral lichen planus via the TRIB2-MAPK signal axis.

Unlabelled: Oral lichen planus (OLP) is a common chronic inflammatory disease in the oral cavity, and has the risk of developing into oral squamous cell carcinoma (OSCC). It is necessary to discover the role of TRIM21 in the pathogenesis of OLP and its underlying mechanism.

Methods: Western bolt and qPCR assays were used to detect the effects of TRIM21 on cellular levels of ERK, p-ERK, AP-1, IL-6, TRIB2, IRF3, and IRF7, while co-immunoprecipitation was performed to verify the interaction between Trim21 and TRIB2 protein.

Research trends and characteristics of oral lichen planus: A bibliometric study of the top-100 cited articles.

Background: Bibliometric analysis highlights the key topics and research trends which have shaped the understanding and management of a concerned disease. The objective of this study was to identify and characterize the most-cited articles on oral lichen planus (OLP), and highlight the analysis of key topics and research trends.

Methods: A comprehensive search was performed and identified in the Scopus database from 1907 to 5 March 2019 for the top-100 most-cited articles on OLP.

Enhanced T-cell proliferation and IL-6 secretion mediated by overexpression of TRIM21 in oral lesions of patients with oral lichen planus.

Backgrounds: To explore the expression and functions of the tripartite motif-containing protein 21 (TRIM21) in oral lichen planus(OLP) lesions.

Methods: Paraffin sections of buccal mucosa samples from 15 cases of reticular oral lichen planus (OLP) patients and 10 healthy controls were used for immunohistochemistry to determine expression and distribution of TRIM21. Buccal mucosae from 11 OLP patients and seven healthy controls were analyzed by qPCR to quantify its gene expression.

Protocells self-assembled by hydroxyapatite nanoparticles: Highly efficient and selective enrichment of chlorophenols in an aqueous environment.

In this paper, amphiphilic hydroxyapatite (HAP) nanoparticles were modified by dibutyl phosphate (DBP) via covalent bonding. The modified HAP particles (m-HAP) were employed as building blocks to construct oil-in-water (O/W) Pickering emulsion, that displayed an excellent performance on the enrichment of organic pollutants dissolved in wastewater by extracting the organic molecules into the oil phase. Environment-friendly organic solvent hexanol was selected as oil phase and three types of monochlorophenol (2-chlorophenol, 3-chlorophenol, 4-chlorophenol) were chosen as model pollutants in simulated wastewater.

Mixed and inhomogeneous expression profile of Th1/Th2 related cytokines detected by cytometric bead array in the saliva of patients with oral lichen planus.

Objective: The aim of this study was to measure T helper (Th) 1/Th2-related cytokine expression in saliva from patients with oral lichen planus (OLP), compared with healthy controls (HC group) and controls with recurrent aphthous ulcers (RAU group).

Study Design: Saliva was collected from 41 patients with OLP, 14 HCs, and 14 controls with RAU for Th1/Th2-related cytokines analysis with cytometric bead array. Disease activity in OLP was recorded by reticulation/keratosis, erythema, and ulceration scores.