Polarization and wavelength multiplexed metalenses address the bulkiness of traditional imaging systems. However, despite progress with numerical simulations and parameter scanning, the engineering complexity of classical methods highlights the urgent need for efficient deep learning approaches. This paper introduces a deep learning-driven inverse design model for polarization-multiplexed metalenses, employing propagation phase theory alongside spectral transfer learning to address chromatic dispersion challenges.
View Article and Find Full Text PDFMetal halide scintillators serve as a compelling substitute for traditional scintillators in X-ray detection and imaging due to their low-temperature fabrication process, high light yield and mechanical flexibility. Nevertheless, the spatial resolution and photoluminescence quantum yield (PLQY) of these films are hindered by the agglomeration and uneven distribution of metal halides crystal particles during the fabrication process. We introduce a modified fabrication approach for metal halide scintillator films involving an additional step of ethyl acetate (EA) treatment, resulting in the preparation of a smooth EA-treated (Ph4P)2MnBr4/Polydimethylsiloxane film.
View Article and Find Full Text PDFBackground: Limited data exists on the link between dietary iron intake and mortality in diabetes. Our investigation aimed to explore how dietary iron intake correlates with overall and cause-specific mortality in diabetic individuals.
Methods: This analysis encompassed 5970 participants with diabetes from the National Health and Nutrition Examination Survey spanning 1999 to 2014.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
July 2024
Objective To investigate the levels of costimulator molecules CD28, CD152/CTLA4, PD-1 and NK cells in peripheral blood of patients with pulmonary tuberculosis (PTB), and to explore the activation of T cell subsets and function of NK cell in PTB patients, as well as the role of T cell costimulatory signaling molecules in the pathogenesis of PTB. Methods Thirty-two PTB patients (PTB group) and 15 health examiners (control group) were recruited.The expression of CD28 and CD152 on peripheral blood T lymphocytes was detected by flow cytometry.
View Article and Find Full Text PDFThe continuous emergence of highly immune-evasive SARS-CoV-2 variants has challenged vaccine efficacy. A vaccine that can provide broad protection is desirable. We evaluated the immunogenicity of a series of monovalent and bivalent adenovirus-vectored vaccines containing the spikes of Wildtype (WT), Beta, Delta, Omicron subvariants BA.
View Article and Find Full Text PDFOrganic luminophores offer great potential for energy harvesting and light emission due to tunable spectral properties, strong luminescence, high solubility, and excellent wavelength-selectivity. To realize their full potential, the lifetimes of luminophores must extend to many years under illumination. Many organic luminophores, however, have a tendency to degrade and undergo rapid photobleaching, leading to the perception of intrinsic instability of organic molecules.
View Article and Find Full Text PDFIntestinal immunity plays a pivotal role in overall immunological defenses, constructing mechanisms against pathogens while maintaining balance with commensal microbial communities. Existing therapeutic interventions may lead to drug resistance and potential toxicity when immune capacity is compromised. Dendrobium officinale, a traditional Chinese medicine, contains components identified to bolster immunity.
View Article and Find Full Text PDFAims: Although low-intensity pulsed ultrasound (LIPUS) combined with disinfectants has been shown to effectively eliminate portions of biofilm in vitro, its efficacy in vivo remains uncertain. Our objective was to assess the antibiofilm potential and safety of LIPUS combined with 0.35% povidone-iodine (PI) in a rat debridement, antibiotics, and implant retention (DAIR) model of periprosthetic joint infection (PJI).
View Article and Find Full Text PDFWe found that the interfacially confined self-assembly of pyrene and phenanthrene glutamides can form strong exciplexes and amorphous superhelices, which show intensity-enhanced and sign-inverted CPL activity with improved quantum yield compared to a pyrene excimer. This work unveils the predominant role of supramolecular nanostructures over molecular configurations on CPL performance.
View Article and Find Full Text PDFIn this Letter, a transfer learning method is proposed to complete design tasks on heterogeneous metasurface datasets with distinct functionalities. Through fine-tuning the inverse design network and freezing the parameters of hidden layers, we successfully transfer the metasurface inverse design knowledge from the electromagnetic-induced transparency (EIT) domain to the three target domains of EIT (different design), absorption, and phase-controlled metasurface. Remarkably, in comparison to the source domain dataset, a minimum of only 700 target domain samples is required to complete the training process.
View Article and Find Full Text PDFObjective: Given the high incidence of pulmonary complications and poor prognosis in patients with multiple rib fractures, we have developed a risk prediction model for pulmonary complications in patients with MRF. In order to identify the high-risk groups prone to pulmonary complications as early as possible, we will intervene in advance and provide targeted interventions to improve patients' quality of life and disease prognosis.
Methods: The prospective cohort study design scheme was used to collect data information based on the hospital's electronic medical record system.
The artificial regulation of the Three Gorges Reservoir (TGR) creates large water level fluctuation zones (WLFZ) that may change the behavior of metals and metalloid in sediment, particularly redox sensitive elements. Mobilization of As, Fe and Mn across the sediment-water interface (SWI) in the TGR as a function of different water depth (periodically and permanently submerged sediments, respectively) was in situ determined by diffusive gradients in thin films (DGT) and high-resolution dialysis technique (HR-Peeper), respectively. The results showed that the mobilization of As was significantly affected by Fe/Mn especially Mn, across the SWI.
View Article and Find Full Text PDFPurpose: Single-stage revision has gained significant attention as a major surgical approach for periprosthetic joint infection (PJI). However, the 90-day mortality and complication profile of single-stage revision is poorly characterized. The purposes of this study were to determine the incidence rates of and identify the risk factors for 90-day postoperative mortality and complications of single-stage revision for chronic PJI.
View Article and Find Full Text PDFRecent genomic studies in adult and pediatric acute myeloid leukemia (AML) demonstrated recurrent in-frame tandem duplications (TD) in exon 13 of upstream binding transcription factor (UBTF). These alterations, which account for approximately 4.3% of AML in childhood and about 3% in adult AML aged <60 years of age, are subtype-defining and associated with poor outcomes.
View Article and Find Full Text PDFPhosphorus (P) conveyed by surface runoff plays an essential role in regulating nutrient balance and primary production in estuarine waters. In this study, basic physiochemical properties, total phosphorus (TP, including speciation), particulate iron (PFe), particulate manganese (PMn), and particulate aluminum (PAl) of the surface water in the Pearl River Estuary (PRE) in different seasons were determined to investigate the spatiotemporal distribution characteristics of P and to identify the crucial factor controlling P migration and transformation in the freshwater-saltwater interaction zone. TP concentrations (28.
View Article and Find Full Text PDFIntroduction: Postpartum depression (PPD), a prevalent public health problem, is a debilitating mental disorder for which preventive interventions could yield dramatic benefits. However, viable approach focusing the prevention of PPD for caesarean section (CS) patients remains limited currently. In recent decades, enhanced recovery after surgery (ERAS) has gradually been implemented in CS and appears to be a potential and favourable preventive intervention for PPD, but systematic evidence on this issue is lacking.
View Article and Find Full Text PDFMedical expulsive therapy demonstrates efficacy in managing ureteral stones in patients amenable to conservative interventions. This meta-analysis aims to evaluate the effectiveness of mirabegron in the treatment of ureteral stones. From conception to November 2023, we examined PubMed databases, the Cochrane Library, Embase, Ovid, Scopus, and trial registries for this systematic review and meta-analysis.
View Article and Find Full Text PDFQ fever is a significant zoonotic disease caused by Coxiella burnetii, an obligate intracellular gram-negative bacterium. Although C. burnetii infection has been identified in various animal species, domestic ruminants serve as the primary reservoirs and main sources of human infection.
View Article and Find Full Text PDFReservoirs play important roles in the drinking water supply for urban residents, agricultural water provision, and the maintenance of ecosystem health. Satellite optical remote sensing of water quality variables in medium and micro-sized inland waters under oligotrophic and mesotrophic status is challenging in terms of the spatio-temporal resolution, weather conditions and frequent nutrient status changes in reservoirs, etc., especially when quantifying non-optically active components (non-OACs).
View Article and Find Full Text PDFRecent genomic studies in adult and pediatric acute myeloid leukemia (AML) demonstrated recurrent in-frame tandem duplications (TD) in exon 13 of upstream binding transcription factor (). These alterations, which account for ~4.3% of AMLs in childhood and up to 3% in adult AMLs under 60, are subtype-defining and associated with poor outcomes.
View Article and Find Full Text PDFCoal seam drilling is a simple, economical, and effective measure commonly used to prevent and control rock burst. Following rock burst, coal exhibits significant dynamic characteristics under high strain-rate loading. Our purpose was to determine the physical processes associated with impact damage to drilled coal rock, and its mitigation mechanism.
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