Resveratrol induces SIRT1-Dependent autophagy to prevent HO-Induced oxidative stress and apoptosis in HTR8/SVneo cells.

Introduction: Pre-eclampsia (PE) is a serious complication of pregnancy, and the likely pathogenic basis of early onset PE are placental dysfunction and increased oxidative stress. Resveratrol (RES) is a potent antioxidant which has shown beneficial effects in many diseases. The aim of this study was to investigate the protective effects of RES against oxidative stress-induced damage in trophoblasts, and elucidate the potential mechanisms.

Magnetically Recyclable FeO@Zn CdS Core-Shell Microspheres for Visible Light-Mediated Photocatalysis.

Magnetically recyclable photocatalyst has drawn considerable research interest because of its importance in practical applications. Herein, we demonstrate a facile hydrothermal process to fabricate magnetic core-shell microspheres of FeO@Zn CdS, successfully using FeO@ZnS core-shell microspheres as sacrificed templates. The as-prepared magnetically recyclable photocatalysts show efficient photochemical reduction of Cr(VI) under irradiation of visible light.

Controlled synthesis of upconverting nanoparticles/CuS yolk-shell nanoparticles for in vitro synergistic photothermal and photodynamic therapy of cancer cells.

Synergistic photodynamic and photothermal therapy of cancer cells is of considerable scientific and technological interest. In this work, we demonstrate a sacrificial template strategy to fabricate yolk-shell nanoparticles combining upconversion nanoparticles (UCNPs) and CuS nanoparticles. Lanthanide-doped upconversion nanoparticles of NaYF:30% Yb,1% Nd,0.

Discovery of [1,2,3]Triazolo[4,5-]pyrimidine Derivatives as Novel LSD1 Inhibitors.

Lysine specific demethylase 1 (LSD1) plays a pivotal role in regulating the lysine methylation. The aberrant overexpression of LSD1 has been reported to be involved in the progression of certain human malignant tumors. Abrogation of LSD1 with RNAi or small molecule inhibitors may lead to the inhibition of cancer proliferation and migration.

[The incidence and mortality of lung cancer among residents in Yangpu district of Shanghai from 2002 to 2010].

Objective: To analyze the incidence and mortality of lung cancer patients among residents in Yangpu District of Shanghai from 2002 to 2010.

Methods: The data of lung cancer cases in permanent residents of Yangpu district were collected from the database of the registration and management system in Shanghai city. Temporal trend in the incidence of lung cancer was analyzed by using annual percent change (APC) mode1.

[The occurrence and survival condition of primary liver cancer among residents in Yangpu district of Shanghai between year 2002 and 2010].

Objective: To analyze the incidence and survival rates of primary liver cancer (PLC) among residents in Yangpu district of Shanghai.

Methods: A total of 9 730 736 permanent residents (male 4 996 390 and female 4 734 346) of Yangpu district in Shanghai were recruited in the study between year 2002 and 2010; among whom 2726 PLC cases were diagnosed and 2427 death cases were certified. The incidence and mortality of PLC were calculated under the analysis of the new PLC cases and death cases between year 2002 and 2010.