Ferroptosis and cuproptosis prognostic signature for prediction of prognosis, immunotherapy and drug sensitivity in hepatocellular carcinoma: development and validation based on TCGA and ICGC databases.

Background: Hepatocellular carcinoma (HCC) is a common malignancy. Ferroptosis and cuproptosis promote HCC spread and proliferation. While fewer studies have combined ferroptosis and cuproptosis to construct prognostic signature of HCC.

[Progress in diagnosis and therapy of thoracic outlet syndrome].

Thoracic outlet syndrome(TOS) are constellation of symptoms caused by compression of the neurovascular bundle including the brachial plexus, the subclavian artery and the subclavian vein at the thoracic outlet region. It includes neurogenic TOS, venus TOS, arterial TOS, and neurogenic TOS is the most common type. TOS has varied manifestations and lack of confirmatory testing, therefore, the diagnosis should be conbination with thorough history, physical examination and associated supplementary examinations.

Carbon-doped SnS nanostructure as a high-efficiency solar fuel catalyst under visible light.

Photocatalytic formation of hydrocarbons using solar energy via artificial photosynthesis is a highly desirable renewable-energy source for replacing conventional fossil fuels. Using an L-cysteine-based hydrothermal process, here we synthesize a carbon-doped SnS (SnS-C) metal dichalcogenide nanostructure, which exhibits a highly active and selective photocatalytic conversion of CO to hydrocarbons under visible-light. The interstitial carbon doping induced microstrain in the SnS lattice, resulting in different photophysical properties as compared with undoped SnS.

Ni-Nanocluster Modified Black TiO with Dual Active Sites for Selective Photocatalytic CO Reduction.

One of the key challenges in artificial photosynthesis is to design a photocatalyst that can bind and activate the CO molecule with the smallest possible activation energy and produce selective hydrocarbon products. In this contribution, a combined experimental and computational study on Ni-nanocluster loaded black TiO (Ni/TiO ) with built-in dual active sites for selective photocatalytic CO conversion is reported. The findings reveal that the synergistic effects of deliberately induced Ni nanoclusters and oxygen vacancies provide (1) energetically stable CO binding sites with the lowest activation energy (0.

Enhanced hydrogen evolution reaction on hybrids of cobalt phosphide and molybdenum phosphide.

Production of hydrogen from water electrolysis has stimulated the search of sustainable electrocatalysts as possible alternatives. Recently, cobalt phosphide (CoP) and molybdenum phosphide (MoP) received great attention owing to their superior catalytic activity and stability towards the hydrogen evolution reaction (HER) which rivals platinum catalysts. In this study, we synthesize and study a series of catalysts based on hybrids of CoP and MoP with different Co/Mo ratio.

Tungsten carbide-nitride on graphene nanoplatelets as a durable hydrogen evolution electrocatalyst.

Alternatives to platinum-based catalysts are required to sustainably produce hydrogen from water at low overpotentials. Progress has been made in utilizing tungsten carbide-based catalysts, however, their performance is currently limited by the density and reactivity of active sites, and insufficient stability in acidic electrolytes. We report highly active graphene nanoplatelet-supported tungsten carbide-nitride nanocomposites prepared via an in situ solid-state approach.

Recent developments in transition metal carbides and nitrides as hydrogen evolution electrocatalysts.

The production of hydrogen by the electrolysis of water, a sustainable and greenhouse-gas-free source, requires an efficient and abundant electrocatalyst that minimizes energy consumption. Interest in transition metal carbides and nitrides has been aroused by their promising properties that make them potential substitutes for Pt-group metals as catalysts for the hydrogen evolution reaction. In this review, we discuss systematically the recent progress in the development of group IV-VI metal carbides and nitrides toward the hydrogen evolution reaction.

Highly stable Pt monolayer on PdAu nanoparticle electrocatalysts for the oxygen reduction reaction.

Stability is one of the main requirements for commercializing fuel cell electrocatalysts for automotive applications. Platinum is the best-known catalyst for oxygen reduction in cathodes, but it undergoes dissolution during potential changes while driving electric vehicles, thus hampering commercial adoption. Here we report a new class of highly stable, active electrocatalysts comprising platinum monolayers on palladium-gold alloy nanoparticles.

An insulator-based dielectrophoretic microdevice for the simultaneous filtration and focusing of biological cells.

Manipulating and discriminating biological cells of interest using microfluidic and micro total analysis system (μTAS) devices have potential applications in clinical diagnosis and medicine. Cellular focusing in microfluidic devices is a prerequisite for medical applications, such as cell sorting, cell counting, or flow cytometry. In the present study, an insulator-based dielectrophoretic microdevice is designed for the simultaneous filtration and focusing of biological cells.

[Treatment and prognosis of malignant ovarian neoplasms complicating pregnancy].

Objective: To summarize the clinicopathological features and prognosis of malignant ovarian neoplasms complicating pregnancy and explore the rational treatment.

Methods: The clinical data of 38 patients with malignant ovarian neoplasms complicating pregnancy were retrospectively analyzed,and the intra-surgical pathological sections were reviewed. International Federation of Gynecology and Obstetrics (FIGO) staging system (1988) was applied.

[Clinical controlled trial on the treatment of comminuted clavicular fracture with acromioclavicular external fixator and clavicle anatomic DCP internal fixation].

Objective: To explore the different therapeutic effects of comminuted clavicular fracture with acromioclavicular external fixtatior and DCP internal fixation.

Methods: There were 768 cases of comminuted clavicular fracture involved in the study. Among them, 528 patients (321 male and 207 female, aged from 15 to 82 years) treated with acromioclavicular external fixator, in which there were 165 cases of three parts fracture and 363 cases of more than three parts fracture; 240 patients (152 males and 88 females, aged from 17 to 64 years) treated with the internal fixation, in which there were 178 cases of three parts fracture and 62 cases of more than three parts fracture.

Enhanced stabilization and deposition of Pt nanocrystals on carbon by dumbbell-like polyethyleniminated poly(oxypropylene)diamine.

Pseudo-dendritic polyethyleniminated poly(oxypropylene)diamine (D400(EI)(20)) was used as a stabilizer and promoter to prepare Pt nanoparticles in aqueous solution, which was then deposited on carbon surface followed by calcination. After being deposited on carbon surface, no Pt(0) could be detected in the solution phase. In all steps, the increasing molar ratio of the amino groups of D400(EI)(20) to H(2)PtCl(6) ([N]/[Pt]) drastically reduced the size and the polydispersity and kept a constant low value after [N]/[Pt] = 20.

Stabilizing effect of pseudo-dendritic polyethylenimine on platinum nanoparticles supported on carbon.

A new type of surfactant with a hydrophile of dendritic polyethylenimine (C(12)(EI)(7)) was synthesized by a cationic polymerization of dodecylamine with aziridine and was used as a stabilizer to prepare Pt colloid, which is then used in situ to prepare carbon-supported Pt nanoparticles. The effects of supporting carbon, surfactant concentration, and calcination time on the nanoparticle size and catalytic performance were determined from the transmission electron microscopic analyses and cyclic voltammograms. In the presence of carbon, the Pt particle size increased slightly with lower C(12)(EI)(7) content, while those with higher C(12)(EI)(7) concentrations remained unchanged.

Self-assembly of gold nanoparticles induced by poly(oxypropylene)diamines.

A series of poly(oxypropylene)diamines D230, D400, D2000, and D4000, having molecular weights of hydrophobic segments of 230, 400, 2000, and 4000, were used as ligands to synthesize self-organized gold nanocrystals. Ligand exchange significantly reduced the average particle size and the polydispersity of nanocrystals, and this effect was more remarkable as the molar ratio of amine groups to Au3+ ions ([N]/[Au3+] ratio) was increased. Under the same [N]/[Au3+] ratio of 100, D2000 generated an ordered 2D-monolayer; however, D230 and D400 colloids formed mainly a densely packed 3D structure with minor 2-D layers, and D4000 presented disordered 3D and 2D structures.

Generation and synthetic uses of stable 4-[2-isopropylidene]-phenol carbocation from bisphenol A.

[reaction: see text] Stable 4-[2-isopropylidene]-phenol carbocation, IPP cation 1, was generated readily by addition of bisphenol A in concentrated sulfuric acid at ambient temperature, and the cation could be used for facile syntheses of 4-isopropenyl phenol (IPP), IPP dimers, and spiro-bisphenol derivatives.

[Recytoreductive surgery for recurrent epithelial ovarian cancer].

Objective: To evaluate the role of recytoreductive surgery (RCRS) in recurrent epithelial ovarian cancer.

Methods: Fifty-five patients who underwent recytoreductive surgery at Peking Union Medical College Hospital between Nov. 1998 and Apr.