Publications by authors named "Chen-Xia Sun"

Article Synopsis
  • - Baicalin has various health benefits, including anti-inflammatory and antibacterial properties, but its role in treating Adriamycin-induced nephrotic syndrome (NS) isn't fully understood.
  • - In a study with rats, researchers found that baicalin improved kidney function and caused significant changes in the expression of 363 genes related to EMT, fibrosis, apoptosis, and inflammation in those with Adriamycin-induced NS.
  • - The findings suggest that baicalin could be a promising treatment for NS by reducing inflammation and fibrosis, indicating potential therapeutic genes for future research.
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Article Synopsis
  • Melittin, found in honeybee venom, shows potential as a treatment for Rheumatoid Arthritis (RA) by reducing inflammation and pain.
  • This study examined melittin's effects on fibroblast-like synoviocytes (FLS) from RA patients, specifically its impact on cell survival, apoptosis, and inflammatory processes.
  • Findings revealed that melittin decreases FLS viability, encourages apoptosis and autophagy, and lowers IL-1β secretion, suggesting it may help protect joints from damage in RA.
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Disordered copper metabolism plays a critical role in the development of various cancers. As a nanomedicine containing copper, cuprous oxide nanoparticles (CONPs) exert ideal antitumor pharmacological effects in vitro and in vivo. Prostate cancer is a frequently diagnosed male malignancy prone to relapse, and castration resistance is the main reason for endocrine therapy failure.

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