- Ganoderma lucidum has valuable compounds like polysaccharides and triterpenoids, but challenges exist with liquid fermentation regarding strain stability and differentiation.
- Researchers used plasma mutation and a unique microbial culture system to develop three mutant strains (YB05, YB09, YB18) that show better growth and production of triterpenoids compared to the original strain.
- The study established a new screening method that effectively identifies beneficial strains for liquid fermentation, with mutants YB05 and YB18 showing significant increases in biomass and triterpenoid production and maintaining stability over five generations.