Ampelopsin attenuates carbon tetrachloride-induced mouse liver fibrosis and hepatic stellate cell activation associated with the SIRT1/TGF-β1/Smad3 and autophagy pathway.

Ampelopsin (Amp), a natural flavonoid found in the vine tea of Ampelopsis grossedentata, exhibited anti-cancer, anti-oxidant, anti-inflammatory, anti-apoptosis and hepatoprotective properties. The current study instigates the protective effect of Amp on carbon tetrachloride (CCl)-induced hepatic fibrosis and explores its underlying mechanisms. The results indicated Amp decreased the levels of liver injury markers.

Magnetic nanochains of metal formed by assembly of small nanoparticles.

Ni nanochains are synthesized with diameters of 150-250 nm and lengths of 0.5-2 microm by assembly of small nanoparticles, which exhibit a magnetic coercivity over two orders of magnitude larger than that of bulk Ni.