Genome-Wide Identification and Role of the Gene Family in Flowering Regulation.

The basic helix-loop-helix () gene family is a crucial regulator in plants, orchestrating various developmental processes, particularly flower formation, and mediating responses to hormonal signals. The molecular mechanism of bamboo flowering regulation remains unresolved, limiting bamboo breeding efforts. In this study, we identified 309 genes and divided them into 23 subfamilies.

The Effect of Cosmetic Makeup on Body Imagery and Anxiety and Depression in Patients Undergoing Postoperative Chemotherapy for Breast Cancer: A Randomized Controlled Study.

The objective was to compare the body images of breast cancer patients undergoing postoperative chemotherapy and the varying degrees of their anxiety and depression. The comparison involved those who received four consecutive cycles of cosmetic makeup and those who did not. Seventy-four breast cancer patients receiving postoperative chemotherapy were randomly assigned to either the control group or the intervention group.

Expression of Iron Metabolism Genes Is Potentially Regulated by DOF Transcription Factors in Leaves.

Transcription factors (TFs) are crucial pre-transcriptional regulatory mechanisms that can modulate the expression of downstream genes by binding to their promoter regions. DOF (DNA binding with One Finger) proteins are a unique class of TFs with extensive roles in plant growth and development. Our previous research indicated that iron content varies among bamboo leaves of different colors.

Organocatalyzed Asymmetric Michael Addition of 3-Fluorooxindole to Vinylidene Bisphosphonates.

Both the 3-fluorooxindole and germinal bisphosphonate structural motifs are prevalent in bioactive molecules because of their associated biological activities. We describe an approach to accessing 3,3-disubstituted 3-fluorooxindoles bearing a geminal bisphosphate fragment through a highly enantioselective Michael addition reaction between 3-fluorooxindoles and vinylidene bisphosphonates. These reactions are catalyzed by a commercially available cinchona alkaloid catalyst, have a broad substrate scope concerning 3-fluorooxindoles, and provide the corresponding addition products in a yield of up to 95% with an enantiomeric excess of up to 95%.

Variability in Leaf Color Induced by Chlorophyll Deficiency: Transcriptional Changes in Bamboo Leaves.

The diversity of leaf characteristics, particularly leaf color, underscores a pivotal area of inquiry within plant science. The synthesis and functionality of chlorophyll, crucial for photosynthesis, largely dictate leaf coloration, with varying concentrations imparting different shades of green. Complex gene interactions regulate the synthesis and degradation of chlorophyll, and disruptions in these pathways can result in abnormal chlorophyll production, thereby affecting leaf pigmentation.

Identification and characterization of the cupin_1 domain-containing proteins in ma bamboo () and their potential role in rhizome sprouting.

Cupin_1 domain-containing protein (CDP) family, which is a member of the cupin superfamily with the most diverse functions in plants, has been found to be involved in hormone pathways that are closely related to rhizome sprouting (RS), a vital form of asexual reproduction in plants. Ma bamboo is a typical clumping bamboo, which mainly reproduces by RS. In this study, we identified and characterized 53 CDP genes and divided them into seven subfamilies.

Ultrasound-guided acupotomy for trigger finger: a systematic review and meta-analysis.

Background: Trigger finger is a common condition in the hand, and ultrasound-guided acupotomy for trigger finger has been widely used in recent years.

Purpose: This study aims to investigate the efficacy and safety of ultrasound-guided acupotomy for trigger finger.

Methods: We searched for relevant studies in the Cochrane Library, China National Knowledge Infrastructure (CNKI), Embase, PubMed, Chinese Biomedical Literature Database (CBM), Wanfang Data, and other resources from their inception to January 2023.

Enantioselective Synthesis of Diarylmethylamines through the Aza-Friedel-Crafts Reaction of 1,3,5-Trialkoxy Benzenes and -Sulfonyl Aldimines Catalyzed by BINOL-Derived Disulfonimides.

A 1,1'-bi-2-naphthol (BINOL)-derived disulfonimide (DSI)-catalyzed enantioselective aza-Friedel-Crafts reaction between 1,3,5-trialkoxy benzenes and -sulfonyl aldimines gives direct access to a series of chiral diarylmethylamines in good yields and good to excellent enantioselectivities (up to 97% ee). This reaction provides a useful protocol for the direct synthesis of diarylmethylamine derivatives.

Coexisting Frailty and Cognitive Impairment as a Predictor of Adverse Outcomes in Older Inpatients After Discharge: Results from a One-Year Follow-Up Study.

Purpose: This study aimed to investigate the combined effects of frailty and cognitive impairment on adverse outcomes, including new falls and new activities of daily living (ADL) dependency over a 1-year follow-up.

Patients And Methods: A total of 311 older hospitalized patients participated in this retrospective observational study and completed a 1-year follow-up. Frailty was assessed by the Clinical Frailty Scale (CFS).

Adsorption of thiotepa anticancer drugs on the CN nanotube as promising nanocarriers for drug delivery.

This paper focused on the efficiency of carbon nitride nanotubes functionalized with alanine amino acid (f-CNNTs) in thiotepa (TPA) anti-cancerous drug delivery via density functional theory (DFT). Pristine CNNTs were incorporated for comparison. TPA was found to spontaneously undergo exothermic adsorption onto the nanostructures.

In(OTf)-catalyzed -α phosphonylation of ,-acetals with triethyl phosphite.

A practical approach to α-aminophosphonates has been developed through an In(OTf)-catalyzed -α phosphonylation of ,-acetals with triethyl phosphite 7. Indoline and isoindoline ,-acetals 6a-6j and 9a-9j and chain ,-acetals 11a-11p were subjected to a Lewis acid catalyzed -α phosphonylation process. As a result, the desired α-aminophosphonates 8a-8j, 10a-10j and 12a-12p were obtained in moderate to good yields.

Stable structures and superconducting properties of Ca-La-H compounds under pressure.

The calcium hydrides and lanthanum hydrides under high pressures have been reported to have good superconducting properties with high-. In this work, the structures and superconductivities of Ca-La-H ternary hydrides have been studied by genetic algorithm and density functional theory calculations. Our results show that at the pressure range of 100-300 GPa, the most stable structure of CaLaHhas asymmetry, in which there is a Hhydrogen cage.

6-Shogaol alleviates CCl4-induced liver fibrosis by attenuating inflammatory response in mice through the NF-κB pathway.

Liver fibrosis is a global health problem caused by a number of diseases related to liver damage. 6-Shogaol is a biologically active substance derived from the rhizome of Zingiber officinale Roscoe with anti-tumor, anti-inflammatory, and antioxidant properties. To explore the effects of 6-Shogaol on liver fibrosis, we used a mouse model of the condition in which mice were injected intraperitoneally with carbon tetrachloride (CCl4) at a dose of 2 mL/kg three times per week for a period of 4 weeks.

Ligustrazine Attenuates Liver Fibrosis by Targeting miR-145 Mediated Transforming Growth Factor-/Smad Signaling in an Animal Model of Biliary Atresia.

To investigate therapeutic target for ligustrazine during liver fibrosis in an ethanol-induced biliary atresia rat model and transforming growth factor- (TGF-) induced hepatic stellate cell activation cell model, and the underlying mechanism, a total of 30 rats were randomly assigned into five groups ( = 6 per group): control, sham, ethanol-induced biliary atresia model, model plus pirfenidone, and model plus ligustrazine groups. The liver changes were assessed using H&E and Masson staining and transmission electron microscopy. Expression of miR-145 and mRNA and protein levels of TGF-/smads pathway-related proteins were detected.

Treatment of Preschool Children With Autism Spectrum Disorder: A Trial to Evaluate a Learning Style Profile Intervention Program in China.

Objective: To investigate whether the provision of learning style profile (LSP) training improves development in preschool children with autism spectrum disorder (ASD) in China and to describe the characteristics of children who benefit from the intervention.

Methods: Eighty-one children aged 36 to 72 months who were diagnosed with ASD for the first time were recruited for the intervention group. All of them received 24 weeks of LSP training, consisting of hospital- and home-based training.

Image enhancement of color fundus photographs for age-related macular degeneration: the Shanghai Changfeng Study.

Aim: To develop and evaluate a new fundus image optimization software based on red, green, blue channels (RGB) for the evaluation of age-related macular degeneration (AMD) in the Chinese population.

Methods: Fundus images that were diagnosed as AMD from the Shanghai Changfeng Study database were analyzed to develop a standardized optimization procedure. Image brightness, contrast, and color balance were measured.

Enantioselective synthesis of 2-indolyl methanamine derivatives through disulfonimide-catalyzed Friedel-Crafts C2-alkylation of 3-substituted indoles with imines.

An asymmetric Friedel-Crafts C2-alkylation between 3-substituted indoles and imines catalyzed by chiral BINOL-derived disulfonimides (DSIs) has been developed. This reaction tolerated a wide range of 3-substituted indoles and imines, affording a series of chiral 2-indolyl methanamine derivatives in good yields with good to excellent enantioselectivities (up to 98% ee). This is a useful protocol for the direct synthesis of 2-indolyl methanamine derivatives.

Skeletal muscle loss is associated with diabetes in middle-aged and older Chinese men without non-alcoholic fatty liver disease.

Background: Skeletal muscle, a key insulin target organ, has been reported to be associated with diabetes mellitus (DM). Compared to non-diabetic patients, diabetic patients have decreased muscle mass and a higher prevalence of sarcopenia, and patients with sarcopenia may be at increased risk of developing diabetes. In individuals with nonalcoholic fatty liver disease (NAFLD), sarcopenia is associated with the severity of fibrosis and steatosis.

Complete chloroplast genome sequence of (Bambusodae).

is mostly produced in south China; usually cultivated on the banks of the rivers and near villages. We determined the complete chloroplast (cp) genome sequence of using Illumina sequencing data. The complete cp sequence is 139,393 bp, include large single-copy (LSC) region of 82,969 bp, small single-copy (SSC) region of 12,874 bp, a pair of invert repeats (IR) regions of 21,775 bp.

Myocardin suppression increases lipid retention and atherosclerosis via downregulation of ABCA1 in vascular smooth muscle cells.

Myocardin (MYOCD) plays an important role in cardiovascular disease. However, its underlying impact on atherosclerosis remains to be elucidated. ATP binding cassette transporter A1 (ABCA1), a key membrane-associated lipid transporter which maintains intracellular lipid homeostasis, has a protective function in atherosclerosis progress.

Gold-Catalyzed Addition--Boc Cleavage-Cyclization of ,-Acetal with Ynamides for Construction of 6-(-Butyldimethylsilyl)oxy-tetrahydropyrrolo[1,2-][1,3]oxazin-1-ones.

A highly efficient gold-catalyzed approach between ,-acetals and ynamides for the construction of 6-(-butyldimethylsilyl)oxy-tetrahydropyrrolo[1,2-][1,3]oxazin-1-ones was developed. This reaction tolerated a wide range of substituted ,acetals and TsN-substituted ynamides, leading to novel heterocycles in moderate to good yields and with excellent diastereoselectivities (dr > 99:1).

3-(2,2-Dioxo-3,4-di-hydro-benzo[][1,2,3]oxa-thiazin-4-yl)-3-fluoro-1-phenyl-indolin-2-one.

The title compound, CHFNOS, contains two chiral carbon centres, but crystal symmetry generates a racemic mixture. The crystal structure features N-H⋯O hydrogen bonding. The sulfonate group is disordered with an occupancy ratio of 0.