SZ-685C inhibits the growth of non-functioning pituitary adenoma by down-regulating miR-340-3p and inducing autophagy.

Background: SZ-685C, an anthracycline compound derived from the mangrove endophytic fungus sp. (No. 1403) collected from the South China Sea, has shown strong anticancer activities.

Induction of apoptosis by oridonin in nonfunctioning pituitary adenoma cells.

Nonfunctioning pituitary adenoma (NFPA) is one of the major subtypes of pituitary adenomas (PA) and its primary treatment is surgical resection. However, normal surgery fails to remove lesions completely and there remains in lack of frontline treatment, so the development of new drugs for NFPA is no doubt urgent. Oridonin (ORI) has been reported to have antitumor effects on a variety of tumors, but whether it could exhibit the same effect on NFPA requires to be further investigated.

CASC15 Gene Polymorphisms and Glioma Susceptibility in Chinese Children.

Objective: Gliomas are the most common tumors in the central nervous system. The cancer susceptibility candidate 15 (CASC15) gene has been reported to be a susceptibility gene for several types of cancer. No studies have been carried out on the predisposing effect of CASC15 gene single nucleotide polymorphisms (SNPs) on glioma risk.

[Effects of economic fruit forest planting on the stability of red soil aggregates in the subtropical hilly area].

The stability of aggregates is of great significance to evaluate water and soil environment in regions plan-ting economic fruit forest. We explored the effects of economic fruit forest types on the structure and stability of soil aggregates in the 0-50 cm soil layer from 5-year-old , , , and forests in the hilly area in northern Hunan. The content, distribution characteristics and stability indices of soil aggregates from each economic fruit forest were quantitatively analyzed by the Shavinov method.